摘要
目的观察米索前列醇用于防治妊高征产后出血的效果。方法选择住院分娩妊高征患者 1 82例 (轻度 48例 ,中度 56例 ,重度 78例 ) ,孕 37～ 41周。随机分为观察组和对照组 ,分别用米索前列醇配合缩宫素和单用缩宫素。结果观察组产后出血发生率及产后 2小时出血量 (经阴道或剖宫产 )均低于对照组 ,两组比较有显著性差异 (P <0 .0 5)。观察组用药后收缩压与舒张压稍有降低 ,但无显著差异 (P >0 .0 5) ;血氧饱和度、心率、平均动脉压两组均无明显改变 (P >0 .0 5)。结论米索前列醇直肠用药配合缩宫素防治妊高征产后出血 ,疗效显著 ,且安全、方便。
Objective To study the effect of misoprostol in preventing and treating postpartum hemorrhage caused by pregnancy induced hypertension. Methods 182 patients with pregnancy induced hypertension, who had pregnancy of 37～41 weeks were admitted to hospital for delivery, were randomly divided into observation group and control group (48, slight; 56, mild; 78, severe). The two groups were treated with misoprostol combined with oxytocin and oxytocin alone, respectively. Results The occurrence of bleeding and the volume of bleeding within 2 hours after delivery were lower in observation group than in control group, with the significance difference between the two groups (P<0.05). The systolic and diastolic blood pressure declined a little in observation group but there was no significant difference (P>0.05). There was no obvious change in saturation of blood oxygen, heart rates, and mean arterial pressure between the two groups (P>0.05). Conclusion Misoprostol combined with oxytocin is safe and convenient to effectively treat patients with postpartum hemorrhage caused by pregnancy induced hypertension.
出处
《中国综合临床》
北大核心
2003年第6期553-554,共2页
Clinical Medicine of China
关键词
米索前列醇
妊高征
缩宫素
产后出血
Misoprostol
Postpartum hemorrhage
Pregnancy induced hypertension
