摘要
目的 研究高钙膳食和维生素D(VD)对高脂致肥大鼠体重水平的影响。方法 将 30只Wistar雄性大鼠随机分为 3组 :A组饲以高脂饲料 ,B组和C组饲以高脂强化钙饲料。饲养 1周后 ,C组大鼠肌肉注射VD 1 5μg/(kg·bw) ,A、B 2组大鼠同时同部位注射同剂量生理盐水 ,连续 2 8d。 结果 B组和C组体重显著低于A组 (P <0 0 1 ) ;B组的大鼠附睾、肾周脂肪重量显著低于A组 (P <0 0 5) ;B组的胆固醇水平显著低于A组 (P <0 0 5)。结论 提示高钙膳食可能影响大鼠血脂水平 ,减少脂肪在腹部的沉积 ,从而起到减轻大鼠体重的作用。未观察到维生素D促进钙的吸收 。
Objective To study the effect of high calcium diets and vitamin D on weight of obese rats fed high-fat diets.Methods Thirty male Wistar rats were divided into there groups and fed different diets randomly.The ten rats of group A were fed the high-fat diets;the ten rats of group B were fed the high-fat diets and calcium;the ten rats of group C were fed the high-fat diets and calcium.After 1 week,the right leg of the gruop C were injected by vitamin D(15?μg/kg·bw),the others was injected physiological salt water solution at the same time.The study lasted 28 days.Results The weight of group B and gruop C were significantly lower than the group A.The epididymal and perirenal fat weight of group B was significantly lower than group A.The cholesterol levels of group B was significantly lower than group A.Conclusion High calcium diets maybe affect blood fat levels by reducing fat store in abdominal to contribute to lose weight of rats.Teh action of vitamin D promoting the absorption of calcium,and affecting the absorption of lipid and blood fat level did not appear.
出处
《中国公共卫生》
CAS
CSCD
北大核心
2003年第6期710-711,共2页
Chinese Journal of Public Health
关键词
钙
血脂
胆固醇
体重
calcium
blood fat
cholesterol
weight
