摘要
目的:观察益气养元颗粒的主要药理作用。方法:选择昆明种小鼠,进行益气生血、镇静安神、免疫功能实验。结果:益气养元颗粒对失血性血虚模型小鼠的血红蛋白(HB)含量降低、红细胞(RBC)数量减少及对化学性损伤引起的白细胞(WBC)降低有一定的恢复和提高作用。与模型组比较差异有显著性意义(P<0.01)。延长气虚小鼠负荷游泳的时间。对注射环磷酰胺所致的免疫功能低下有一定的增强作用。提高吞噬指数(K)与模型组比较差异有显著性意义(P<0.05)。缩短小鼠睡眠潜伏期,延长小鼠睡眠时间,与模型组比较差异有显著性意义(P<0.05)。结论:益气养元颗粒具有一定的补血益气、镇静安神、增强机体非特异性免疫功能的作用。
Objective: To study the principal pharmacodynamics of Yiqi Yangyuan Granules. Methods: Selected mice to conduct the experiments of replenishing qi and blood, tranquilizing and allaying excitement and immunity. Results: Yiqi Yangyuan Granules obviously increased the content of haemoglobin (HGB) and the counts of red blood cell (RED) in mice on deficiency of blood. Increased the counts of white blood cell (WBC) in mice injured by chemicals. Yiqi Yangyuan Granules also significantly extended the swimming time of the mice on deficiency of qi. Enhanced the immunication in mice, raised peritoneal macrophage phagecytice. Obviously shorted the incubation period of sleeping in mice and extended the sleeping time. Conclusion : Yiqi Yangyuan Granules had the effects on replenishing qi and blood, tranquilizing and allaying excitement. Enhanceing the nonspecific immunity.
出处
《中国中医药信息杂志》
CAS
CSCD
2003年第5期26-28,共3页
Chinese Journal of Information on Traditional Chinese Medicine
