摘要
目的 观察白细胞介素 8(IL 8)、肿瘤坏死因子 α(TNF α)在沙眼衣原体 (CT)所致非淋菌性尿道炎(NGU)患者血清中的变化及在临床表现中的作用。方法 采用双抗体夹心酶联免疫吸附试验 (ELISA)检测NGU患者治疗前后血清IL 8、TNF α水平并与正常对照相比较。结果 NGU患者治疗前血清IL 8、TNF α水平明显高于正常对照 ,而治疗后与正常对照相比差异无显著的统计学意义。结论 IL 8、TNF α可能在CT感染的发生、发展中起重要作用。
Objective To observe change in serum levels of IL-8 and TNF-α and their association with clinical manifestations in patients with nongonococcal urethritis caused by Chlamydia trachomatis.Methods The serum levels of IL-8 and TNF-α were measured by double antibody sandwich ELISA in patients before and after the treatment,compared with those in normal controls.ResultsThe serum levels of IL-8 and TNF-α in patients before the treatment were higher than these in normal controls.However,there was no statistic difference between these patients after treatment and normal controls.Conclusion IL-8 and TNF-α may play an important role in the occurrence and development of infection of Chlamydia trachomatis.
出处
《中国艾滋病性病》
CAS
2003年第2期93-94,共2页
Chinese Journal of Aids & STD
