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透明质酸-壳聚糖-明胶复合体系对L929细胞凋亡和细胞周期的影响 被引量:6

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摘要 在壳聚糖-明胶体系中引入透明质酸,通过磷脂酰基醇(PI)细胞周期分析和膜连蛋白-异硫氢酸荧光素(annexin V-FITC)与PI复染法检测细胞凋亡,结果表明:透明质酸的加入可以缩短细胞在壳聚糖-明胶材料表面的适应时间,使细胞尽快进入正常的细胞周期;同时,透明质酸可以有效地抑制材料触发的细胞凋亡.因此,透明质酸可以有效地提高壳聚糖-明胶体系的细胞相容性,有利于生物材料的仿生化.
出处 《科学通报》 EI CAS CSCD 北大核心 2003年第9期917-920,共4页 Chinese Science Bulletin
基金 国家重点基础研究发展规划资助项目(批准号:G199954305)
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