摘要
目的 对上海地区患者中不规则抗体检出情况进行回顾性总结。方法 对 2 0 0 0年以来上海各医院送检的免疫血液学标本 2 1 49例 ,应用盐水、抗球蛋白法、聚凝胺法检测不规则抗体。结果 共鉴定确认血型不规则抗体 2 2 0例。其中自身抗体 66例、确定同种特异性抗体 1 5 4例 ,分别为 :抗 -D41例、抗 -E3 7例、抗 -c E1 9例、抗 -Ce4例、抗 -CD3例、抗 -c4例、抗 -M 1 5例、抗 -N 3例、抗 -P1 2例、抗 -Lea 1例、抗 -Leb 4例、抗 -Lex 1例、抗 -Mur 3例、抗 -S 2例、抗 -HI 1 1例、抗 -Jkb 1例、抗 -Fyb 1例、抗 -Tja1例、抗 -I1例。结论 检出的不规则抗体与国外数据存在较大差异 ,国外常见的抗 -K、抗 -Fya 在国内较少见。产生抗体的患者 (不包括孕妇 )以女性居多。
Objective A retrospective study was performed to estimate the frequency and specificity of clinically significant irregular RBC antibodies in hospitalized patients in Shanghai.Methods 2 149 blood samples were collected from hospitals in Shanghai.Modified polybrene test and conventional serologic methods were used for the identification of antibody specificity.Results Clinically significant irregular antibodies were found in 220 patients (excluding cold autoantibodies,ABO system antibodies and unconfirmed antibodies).66 samples were autoantibodies,other were alloantibodies.The qualities of alloantibodies found among patients were:anti D 41,anti E 37,anti cE 19,anti Ce 4,anti CD 3,anti c 4,anti M 15,anti N 3,anti P 12,anti Le a1,anti Le b4,anti Le x1,anti Mur 3,anti S 2,anti HI 11,anti Jk b 1,anti Fy b 1,anti Tj a 1,anti I 1.Conclusion Our data showed significant difference compared with Caucasian data.We had found more anti Μ,anti HI and less anti P 1,anti Lewis,anti K,anti Fy a.And we also had found that irregular antibodies presented more frequently in female samples than in male's.
出处
《临床输血与检验》
CAS
2003年第2期103-105,共3页
Journal of Clinical Transfusion and Laboratory Medicine
