摘要
应用分子生物学核酸杂交技术,以人乳头瘤病毒HPV6及HPV11型混合探针对食管ECA109鳞癌细胞株进行DNA斑点杂交。检测结果为阳性。为HPV与食管癌关系的研究进一步提供了证据。
Human esophageal squamous cancer cell line (ECa109)was analyzed by dot-blot hybridization to demonstrate the presence of human papillomavirus(HPV)infection,using a mixed DNA probe containing HPV types 6 and 11. The result was HPV-DNA-positive. The present study provides further evidence for the relation between HPV DNA and esophageal cancer.
出处
《河南肿瘤学杂志》
1992年第2期8-9,65,共2页
Henan Journal of Oncology
关键词
分子杂交
人乳头瘤病毒
食管肿瘤
esophageal cancer
cell line
molecular hybridization
human papillomavirus