摘要
目的制作一种新的猫脑损伤后持续性植物状态模型,观察其临床特征。方法将40只猫行硬膜外水囊置放术,然后向水囊内注入无菌水直到昏迷,并对动物模型进行评估。结果手术1个月后,有12只猫处于植物状态,动物模型的临床表现、体征等与持续性植物状态患者相近。结论本实验制作的持续性植物状态动物模型与临床患者相似,是一种比较理想的持续性植物状态动物模型。
Aim To make a continuous vegetative stat e animal model after brain injury of cat to observe i ts clinical character.Methods Epidural water sac installation were carried out in 40cats,then saline were pure i nto the sacs until coma and the evaluatio n of the animals were made.Results There were 12cats in the vegetative s tate 1month after operation.clinic al manifestation,signs were similar t o PVS patients.Conclusion Continuous PVS animal models are similar to that of clinical patients and was an ideal animal model of PVS.
出处
《中国临床康复》
CSCD
2003年第7期1060-1061,共2页
Chinese Journal of Clinical Rehabilitation
基金
全军医学科研"十五"计划重大项目(01Z054)
河南省高校杰出科研人才创新工程项目(2001KYCX003)~~
