摘要
目的 了解深圳地区医院临床分离菌的耐药情况。方法 2 0 0 1年 1月～ 2 0 0 2年 6月 ,本院临床分离菌用Kirby Bauer法进行药敏试验。 结果 1734株细菌中革兰阳性菌占 40 .6 %,革兰阴性菌占 5 9.4%。最常见的临床分离菌是凝固酶阴性葡萄球菌、大肠埃希菌、铜绿假单胞菌等 ;MRSA和MRCNS分别为 37.8%和 78.8%;粪肠球菌耐万古霉素株 7.6 %;大肠埃希菌中产ESBLs株占 34.9%,肺炎克雷伯菌占 34.2 %;产ESBLs菌株对大多数抗菌药物的耐药率 (除碳青酶烯类外 )均显著高于非产ESBLs株。结论 细菌耐药性仍是目前临床上的难题 ,需采取积极措施 ,减缓细菌耐药性的增长。
OBJECTIVE To investigate the bacterial resistance of clinical isolates from Shenzhen hospitals. METHODS Antimicrobial susceptibility of the clinical isolates collected from Jan 2001 to Jun 2002 were tested by Kirby-Bauer method. RESULTS In 1 734 clinical isolates, Gram positive organisms accounted for 40.6%, Gram negative ones were 59.4%. MRSA and MRCNS accounted for 37.8% and 78.8% of Staphylococcus aureus and coagulase negative staphylococci, respectively, no vancomycin resistant strains were found. 7.6% of Enterococcus faecalis was vancomycin resistant strains. The ESBLs producing strains accounted for 34.9% in Escherichia coli and 34.2% in Klebsiella pneumoniae. The resistance rates of ESBLs producing strains to most antimicrobial agents (except carbapenems) were much higher than those of non ESBLs-producing strains.CONCLUSIONS Bacterial resistance is still more serious than before. A unanimous effective strategy for this problem is urgently needed.
出处
《中华医院感染学杂志》
CAS
CSCD
2003年第4期363-365,共3页
Chinese Journal of Nosocomiology
