摘要
目的 探讨黄杆菌致下呼吸道感染的临床特点、危险因素和对抗生素的敏感性。方法 对 2 4例黄杆菌致下呼吸道感染患者的临床、痰细菌培养及药敏结果进行回顾性分析。结果 全部病例均为院内感染。 >60岁者 16例 (66.6% )。患有 2种或 2种以上基础疾病者 14例 (5 8.3 % ) ;2 4例发病前均应用多种抗生素 ;应用糖皮质激素或免疫抑制剂者 13例 (5 4 .0 % ) ;侵袭性治疗 9例 (3 7.5 % ) ;雾化吸入 10例 (41.6% )。病死率 3 3 .3 %。临床症状及X线表现无特异性。药敏实验呈现多重耐药。结论 老年、基础疾病多、免疫力低下、长期应用抗生素、侵袭性治疗及雾化吸入为黄杆菌下呼吸道感染的危险因素。临床症状重 ,耐药率高 。
Objective To investigate the clinical characteristic,risk factors and antibiotic susceptibilities of 24 cases with lower respiratory infection caused by Flavobacteria.Methods Retrospective study of the clinical data of 24 cases of lower respiratory tract infection caused by Flavobacteria were done.And susceptibilities to antibiotics were assessed by the Kirby Bauer method.Results All of the 24 cases were nosocomical infection.66.6% of the cases aged>60 years old; 58.3 % of the cases had 2 kinds or more than 2 underlying disease;24 cases had the history of taking many kinds of antibiotics,54.0% had glucocorticoids or immunity inhibitors;37.5% had invasive treatment and 41.6% had inhaler therapy with atomizer.No specific clinical manifestations and chest X ray appearance were identified.The drug sensitivity tests demonstrated that these strains were multiresistant to antibiotics.Conclusions Risk factors of lower respiratory infection by Flavobacteria included old aged,multiple underlying disease,immunodeficiency,abuse of antibiotic and invasive managements.Its clinical manfestations were serious.It is multiresistant to antibiotics.The prognosis is poor.Ciprofloxacin,Cefoperazone, Piperacillin,Piperacillin sulbactam sodium and Amoxicillin clavulanic acid are effective in treating lower respiratory tract infection caused by Flavobacteria.
出处
《北京医学》
CAS
北大核心
2003年第2期109-110,共2页
Beijing Medical Journal
