摘要
Objectives: During visual stimulation, the elevated metabolism rate will coupl e with increase of blood flow velocity(BFV) in posterior cerebral artery(PCA). T his study with TCD was aimed to investigate whether the coupling might change ac cording to the different vasoneuronal conditions. Methods: Ninety-nine voluntee r s including 24 hypertension(HT) patients and 2 patients suffering from both HT a nd diabetes mellitus(DM) were enrolled in this trial. BFV and pulse indexes(PI) in P2 segments of PCA on both sides were monitored during visual stimulation. Re sults: In all subjects, Mean BFV increased and PI went down in response to visua l stimulation. The percentages of changes (ΔV and ΔP) of both mean BFV and PI we re larger in young group(<55 years old) than in old one(≥55 years old). There w a s significant positive correlation between ΔV and ΔP. Multivariated re gression a nalysis did not show HT and DM, but age related to ΔV(ΔP). We did not find signi ficant difference of ΔV(ΔP) between left and right sides. Conclusions: Blood flo w velocity in PCA P2 segment increased due to decreased cerebrovascular resistan ce during visual stimulation and the response weakened with aging of the patient .
Obiectives:During visual stimulation,the elevated metabolism rate will couple wity increase of blood flow velocity(BFV) in posterior cerebral artery(PCA),This strudy with TCD was aimed to investigate whether the coupling might change according to the different vasoneuronal conditions.Methods:Ninety-nine volunteers including 24 hypertension(HT) patients and 2 patients suffering from both HT and diabetes mellitus (DM) were enrolled in this trial.BFV and pulse indexes(PI) in P2 segments of PCA on both sides were mon-itored during visual stimulation.Results:In all subjects,Mean BFV increased and PI went down in response to visual stimulation.The percentages of changtes(△V and △P) of both mean BFV and PI were larger in young group(<55 years old)than in old one(≥55 years old),There was significant positive correlation be-tween △V and △P.Multivariated regression analysis did not show HT and DM,but age related to △V(△P).We did not find significant difference of △V(△P) between left and right sides,Conclusions:Blood flow ve-locity in PCA P2 segment increased due to decreased cerebrovascular resistance during visual stimulation and the response weakened with aging of the patient.
