摘要
目的 考察钛膜引导牙种植体 HA颗粒周围骨组织再生的作用。方法 在狗的下颌骨区制备种植窝及人工骨缺损区后 ,植入 HA涂层钛种植体 ,用钛片将骨缺损区平均隔离成两部分 ,一部分植入 HA颗粒 ,另一部分作为空白对照 ,于缺损区上覆盖钛膜 ,种植后第 4、8、12周分别作组织学切片 ,观察种植体周围形态学。结果 在第 4周 ,种植体周围有明显的骨生长 ,第 12周时骨量生成增多 ,骨的结构与周围的板状骨相似。结论 钛膜可维持膜下间隙的存在 ,可作为膜引导的材料 。
Objective To evaluate the titanium membrane guided bone tissue regeneration around implant and HA granules. Methods Three adult cross bred dogs were used. In the animal's mandible, man made bone damaged regions (diameter 6.5 mm, depth 4 mm) being concentric with the implant holes were prepared. The implants were planted into the holes and were rendered to separate the damaged regions into two parts with two titanium sheets. One part was filled with HA granules while the other with nothing. Histological evaluation was done at 4, 8 and 12 weeks of implantation. Results The bone around the implants grew obviously at 4 weeks; the bone grew more and the structure of the bone was similar to that of the normal bone at 12 weeks. Conclusion As a new type of GTR materials, titanium membrane can keep the existence of spaces underneath. HA granules can give guiding effects to bone tissue regeneration.
出处
《四川大学学报（医学版）》
CAS
CSCD
北大核心
2003年第2期267-269,共3页
Journal of Sichuan University(Medical Sciences)
基金
卫生部优秀青年科技人才专项科研基金 ( 970 5 1)资助
关键词
种植体
膜引导骨组织再生
HA颗粒
钛膜
Implant Guided tissue regeneration HA granules Titanium membrane
