摘要
目的探讨低分子肝素在预防下肢静脉曲张术后深静脉血栓形成方面的临床效果。方法将2011年1月至2014年12月期间于笔者所在医院行静脉曲张手术的611例患者随机分为2组:研究组288例,下肢静脉曲张术后采用低分子肝素预防性治疗;对照组323例,术后不采用任何抗凝药物治疗。比较2组患者深静脉血栓形成和并发症发生情况。结果对照组深静脉血栓的发生率高于研究组(P<0.05)。两组病人均未出现内脏出血或硬膜外出血。结论采用低分子肝素预防下肢静脉曲张术后下肢深静脉血栓形成具有良好的临床效果和安全性,值得临床推广应用。
Objective To investigate the effect of low-molecular-weight heparin(LMWH) in prevention deep venous thrombosis( DVT) after the operation of lower extremity varicose vein. Methods From January 2011 to December 2014,611 patients who accepted the operation of lower extremity varicose vein were divided to 2 groups at random. Patients in control group(n=323) were not given low-molecular-weight heparin or other anticoagulant drugs before and after operation, and patients in study group(n=288) were given low-molecular-weight heparin calcium by subcutaneous injection from the first day after operation.The deep venous thrombosis and complications were compared between the 2 groups. Results The incidence of DVT in control group was higher than that in study group(P<0.05),and there was no difference between the two groups in incidence of incision bleeding and(or) subcutaneous hematoma (P>0.05). No patient suffered from visceral hemorrhage or epidural hemorrhage in both groups. Conclusion The therapy of the low molecular weight heparin after the operation of lower extremity varicose vein can safely reduce the incidence of DVT, and It is worthy of clinical application.
出处
《临床普外科电子杂志》
2015年第1期25-28,共4页
Journal of General Surgery for Clinicians(Electronic Version)
关键词
低分子肝素
下肢静脉曲张
深静脉血栓
Low-molecular-weight heparin
Lower extremity varicose vein
Deep venous thrombosis
