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腮腺良性肿瘤浅叶部分切除术与浅叶切除术的循证医学分析 被引量:18

Partial superficial parotidectomy versus superficial parotidectomy for treatment of parotid benign tumors:evidence-based medicine analysis
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摘要 目的:比较腮腺浅叶部分切除术(PSP)和腮腺浅叶切除术(SP)的术后复发率及并发症发生率,为临床治疗腮腺浅叶良性肿瘤选择合适的术式提供理论依据。方法:在Pubmed、CNKI和万方数据库中检索比较PSP和SP手术方法的相关文献,采用RevMan 5.0软件进行Meta分析。结果:获得24篇文献用于Meta分析,共包括2 795例患者,其中1 301例接受PSP,1 494例接受SP。PSP和SP的术后复发率分别为1.14%(10/874)和0.6%(6/993),差异无统计学意义;PSP和SP术后暂时性面瘫的发生率分别为11.6%(122/1 052)和27.37%(350/1 279),永久性面瘫的发生率分别为1.04%(6/579)和4.46%(31/695),Frey综合征的发生率分别为9.20%(95/1 033)和30.32%(409/1 349),涎瘘的发生率分别为5.38%(37/688)和11.25%(65/578),PSP较SP发病率明显降低。结论:与SP相比,PSP并发症发生率低,而肿瘤的复发率并没有提高,提示在适应证选择正确的情况下,PSP可以取代SP用于腮腺良性肿瘤的治疗。 Objective:The aim of this study is to systematically assess the postoperative outcomes of partial superficial parotidectomy(PSP)and superficial parotidectomy(SP)by systematic literature review and Meta-analysis,and to provide a theoretical basis for the selection of the appropriate surgical approach in clinical process.Method:Relevant studies that compared the outcomes of PSP and SP for the parotid benign tumors were searched in Pubmed,CNKI and Wanfangdata databases,and Meta-analysis was performed using software RevMan 5.0.Result:24 studies were selected for the Meta-analysis.A total of 2 795 participants were included in those studies,of whom 1 301 underwent PSP and 1 494 underwent SP.The recurrence rates for PSP and SP were 1.14%(10 of874)and 0.6%(6 of 993),respectively.There were no statistically significant difference in recurrence rate between PSP and SP.The rates of transient facial nerve paresis for PSP and SP were 11.60%(122 of 1 052)and27.37%(350 of 1 279),respectively.The rates of permanent facial nerve paralysis for PSP and SP were 1.04%(6 of 579)and 4.46%(31 of 695),respectively.The incidences of Frey’s syndrome in PSP group and SP group were9.20%(95 of 1 033)and 30.32%(409 of 1 349),respectively.The rate of salivary fistulafor PSP and SP were5.38%(37 of 688)and 11.25%(65 of 578).PSP could reduce the risk for complications compared with SP.Conclusion:This systematic review with meta-analysis suggests that PSP has a similar recurrence rate as SP,but PSP can significantly reduce the postoperativecomplications.
作者 张敏 贾志宇 刘树妍 赵云转 屈鹏飞 陈彪 ZHANG Min;JIA Zhiyu;LIU Shuyan;ZHAO Yunzhuan;QU Pengfei;CHEN Biao(Medical College of Zhangjiakou University,Zhangjiakou,075000,China;Department of O ral and Maxillofacial Surgery,the Second Hospital of Hebei Medical University;Department of Obstetrics and Gynecology,Women and Children Health Care Hospital of Donggang,Rizhao)
出处 《临床耳鼻咽喉头颈外科杂志》 CAS 北大核心 2019年第9期875-882,共8页 Journal of Clinical Otorhinolaryngology Head And Neck Surgery
关键词 腮腺肿瘤 腮腺浅叶部分切除术 腮腺浅叶切除术 Meta分析 parotid neoplasms partial superficial parotidectomy superficial parotidectomy Meta-analysis
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