摘要
目的 体外观察胃石的形成过程 ,以探讨胃石症的可能发病机制 ;观察果胶酶治疗胃石症的临床效果。方法 (1 )体外实验 :①组。将山楂、柿子每样 2 5g ,每样 4份 ,粉碎后置入 2组新鲜胃液容器内 ,②组。在上述容液内再加入 30度白酒 50ml,两组同时置入 37℃恒温箱内 ,观察胃石形成的经过及时间 ;胃石形成后 ,再加入果胶酶 2g ,观察其解聚过程及时间。 (2 )临床应用 :用果胶酶治疗 54例胃石症病人。结果 (1 )体外试验 :不加白酒的山楂平均凝结时间需 2 3min ,柿子需 2 5min。加白酒的山楂平均凝结为 1 4min ,柿子为 1 9min ;加果胶酶平均 1 7min后凝块逐渐呈斑状松动 ,脱落。完全散开平均需 34min。加与不加白酒其解聚过程和时间无明显差别。 (2 )临床应用 :54例胃石症病人服用果胶酶 6h后再行钡餐检查见胃石完全散结 ,消失。结论 山楂或 /和柿子在胃液作用下可形成胃石。果胶酶治疗胃石症有良效 ,消石快 ,方法简便 ,无毒副作用。
Objective To determine the pathological mechanism of gastrolithiasis formation in vitro and the effects of pectinase on gastrolithiasis. Methods The test in vitro was divided randomly into two groups:(1) Haws and persimmons(25g respectively) were chewed and put into two clean containers filled with fresh gastric juice.(2) Wine containing 30% alcohol(50ml) was added to the container. Each group included 4 collections.All two groups were placed in 37℃ calorstat box to observe the course and time of gastrolith formation. After gastrolith formation, 2g pectinase was added to the container and observed the decomposition of pectinase to gastrolith and the time was recorded. The effects of pectinase on 54 patients with gastrolithiasis were also investigated. Results The mean time of haws juice coagulation and persimmons was 23 minutes and 25 minutes respectively in the group without wine; but in the group with wine, the mean time of haws juice coagulation and persimmons was 14 minutes and 19 minutes respectively. After adding pectinase, the mean time of clot initiated decomposition was about 17 minutes in both groups, but complete decomposition needed 34 minutes. All the 54 patients with gastrolithiasis who received pectinase were cured.The gastrolith disappeared 6 hours after taking pectinase confirmed by barium meal examination. Conclusions Haws and/or persimmons mixed with gastric juice could induce gastrolith formation. The effects of pectinase on patients with haws or persimmons gastrolithiasis are good, this therapeutic procedure is simple, and the gastrolith resolves quickly.Pectinase may be widely used in the treatment of gastrolithiasis.
出处
《中国普通外科杂志》
CAS
CSCD
2003年第1期22-24,共3页
China Journal of General Surgery
