摘要
目的 对我院 4年来临床分离的葡萄球菌属的耐药情况及有关抗菌药物的用量进行统计分析 ,为临床合理使用抗菌药物 ,减少细菌耐药性提供参考。方法 对所分离的葡萄球菌属的药敏情况和抗菌药物的用量分别进行统计。结果 金黄色葡萄球菌对一代头孢和红霉素的耐药率同文献报道 ,凝固酶阴性葡萄球菌的临床分离率和耐药率均高于金黄色葡萄球菌 ;青霉素、头孢唑林、红霉素、环丙沙星和复方新诺明用量较大。结论 4年来葡萄球菌属的耐药率虽然有所波动 ,但总体呈上升趋势 。
OBJECTIVE To investigate the relationship between drug resistance of Staphylococcus and the amount of certain antibiotics used in our hospital during the last 4 years. METHODS Retrospective analysis of drug resistance rate of Staphylococcus and the amount of antibiotics used were made respectively. RESULTS The resistance rate of Staphylococcus aureus to the first generation of cephalosporins and erythromycin is similar with that reported in litaretare, and the number of strains separated and resistance rate of coagulase negative Staphylococcus are both higher than S. aureus. Penicillin, cefazolin, erythromycin, ciprofloxacin and SMZco were more widely used. CONCLUSIONS Although the resistance rate of Staphylococcus varies in the 4 years, in general it′s getting higher, and is somewhat related with the amount of antibiotics used.
出处
《中华医院感染学杂志》
CAS
CSCD
2003年第1期62-63,共2页
Chinese Journal of Nosocomiology