摘要
目的 评价腹腔镜下卵巢电凝术治疗难治性多囊卵巢综合征 (Polycysticovariansyndrome,PCOS)的效果。 方法应用电视腹腔镜对 16例促排卵方案治疗无效的PCOS行卵巢电凝术 ,观察术后排卵情况及对促排卵药物的敏感性 ,比较术后血清促卵泡生成素 (FSH)、黄体生成素 (LH)、睾酮 (T)、雌二醇 (E2 )水平的变化。 结果 16例卵巢活检经病理诊断均为多囊卵巢。术后患者血清中LH和T均较术前明显下降 (t=14 75 ,P <0 0 1;t=13 2 0 ,P <0 0 1) ,LH/FSH比值 ( 1 3± 0 5 )趋于正常。 10例 ( 6 2 5 % )术后 2周期内自然行经 ,余 6例术后未自然恢复排卵在给氯米芬后全部促排卵成功。 结论 药物促排卵方案治疗无效的PCOS可选择卵巢电凝术进行促排卵治疗。
Objective To evaluate the efficacy of laparoscopic ovarian electrocautery in refractory polycystic ovarian syndrome (PCOS). Methods A total of 16 PCOS patients who had no response to ovulation-inductive therapy were treated by ovarian electrocautery via laparoscope. After surgery, the ovulation as well as response to ovulation-inductive drugs was observed. The serum concentrations of FSH, LH, T, E 2 before and after operations were respectively compared. Results All 16 cases were pathologically diagnosed as polycystic ovary. There were significant decreases in luteinizing hormone (LH) and testosterone (T) after operations (P<0.01, t=14.75, t=13.20). And LH/FSH ratio was close to the normal value (1.3±0.5). Menstruations occurred in 10 patients (62.5%) within 2 cycles after operations. The other 6 patients had no spontaneous ovulations after electrocautery, but ovulations were induced successfully by the stimulation of clomiphane. Conclusions Laparoscopic ovarian electrocautery can be selected in PCOS patients who have no response to ovulation-inductive drugs .
出处
《中国微创外科杂志》
CSCD
2003年第2期114-115,共2页
Chinese Journal of Minimally Invasive Surgery
关键词
腹腔镜
卵巢电凝术
治疗
难治性多囊卵巢综合征
Polycystic ovary syndrome Laparoscopy Ovarian electrocautery Ovulation-induction
