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同种异体骨移植治疗骨缺损的临床应用

Clinical application of allograft in the treatment of bone defects
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摘要 目的 观察异体骨移植治疗骨缺损的临床疗效。方法  2 1例骨缺损病人 ,年龄 7至 5 6岁 ,创伤性骨缺损 15例 ,肿瘤性骨缺损 6例 ,采用山西省医用组织库提供的同种异体骨移植 ,其中大段骨移植 1例 ,骨块 +骨条移植 11例 ,骨条移植 9例 ,术后观察切口愈合等级 ,免疫排斥反应的表现 ,骨缺损愈合情况及异体骨移植的并发症。结果  2 1例病人随访 2至 18个月 ,切口甲级愈合 16例 ,乙级愈合 4例 ,术后感染丙级愈合 1例。移植骨愈合 19例 ,移植骨部分吸收 1例 ,1例随访时间 65天 ,移植骨尚未愈合。结论 小块异体骨移植可获得自体骨移植的同样疗效 ,未观察到明显的免疫排斥反应 ,大段骨移植疗效尚待观察。 s objective To investigate the clinical effects of allograft in the treatment of bone defects.Methods:21 cases of patients including 15 cases of traumatic bone defects and 6 cases of tumorous bone defects,aged 7 to 56 years old,were treated by allograft which come from Medical Tissue Bank of Shanxi Province in china,in which 1 case of long segmental allograft?11 cases of bone block and bone strip allograft and 9 cases of bone strip allograft postoperative wound union?manifestation of immuno-rejection?union of bone defects and complication were observed.Results:21 cases were followed for 2 to 18 months.incision union of the first rate happened in 16 case,the second rate in 4 cases and 1 case showed postoperative infection of wound.19 cases displayed union of allograft and 1 case showed segmental resorption.1 case was followed for 65 days,butnon-union happened.Discussion:Small piece of allograft can receive the same therapeutic results as that of autograft and no obvious immuno-rejection was found.The effect oflarge segmental allograft is waiting for observation.
出处 《海南医学》 CAS 2003年第3期6-8,共3页 Hainan Medical Journal
关键词 同种异体骨移植 治疗 骨缺损 临床应用 疗效 创伤性 肿瘤性 免疫排斥反应 并发症 Allograft,Bone Transplantation,Bone defects,Therapeutic result.
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  • 1黄传书,中华微生物学和免疫学杂志,1992年,12卷,37页 被引量:1
  • 2黄传书,中华微生物学和免疫学杂志,1991年,11卷,373页 被引量:1

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