摘要
目的探讨胃肠内补液联合静脉补液对糖尿病酮症酸中毒 (DKA)的疗效。方法将 12 0例DKA患者随机分为两组 ,治疗组 6 0例采用胃肠内补液联合静脉补液治疗 ,对照组 6 0例采用单纯性静脉补液治疗 ,观察两组患者治疗前后血生化及尿酮体消失时间等指标的变化。结果治疗组治疗 2 4h后的血糖、血钾、血钠均较治疗前明显下降 (P <0 .0 5 ) ;与对照组相比 ,治疗组的电解质及二氧化碳结合力恢复正常的时间较快 ,尿酮体消失早 ,昏迷患者清醒早 ,静脉补液量少 ,无一例发生脑水肿 ,肺水肿和低血钾等并发症。结论对DKA患者除采用静脉输液外 ,加用胃肠内补液更简便易行 。
ObjectivesTo explore the therapeutic efficacy of combined fluid infusion through gastrointestinal tract plus intravenous Route for diabetic ketoacidosis (DKA).MethodsOne hundred and twenty patients with DKA were randomly divided into two groups:①Treated group,sixty cases, combined fluid infusion through gastrointestinal tract plus intravenous route was given;②Control group,another sixty cases, intravenous infusion was scheduled only. The changes of blood biochemical parameters and excretion of urinary ketone bodies in both groups were observed before and after therapy. ResultsIn the treated group, the blood levels of glucose, potassium and sodium decreased obviously and returned to normal in 24 hours after treatment,as compared with the control group(P<0.05). The blood contents of electrolytes and carbon dioxide combining power in patients of this group returned to normal more quickly, urinary ketone bodies disappeared earlier, and their consciousness recovered rather rapidly; in addition,a lesser volume of intravenous infusion was required. No complications such as cerebral edema,pulmonary edema and hypokalemia occurred.ConclusionFluid infusion through gastrointestinal tract together with intravenous route used for DKA is simple, safe and effective.
出处
《医学临床研究》
CAS
2003年第3期172-174,共3页
Journal of Clinical Research
