摘要
目的 探讨急性脑梗死与血管内皮生长因子 (VEGF)的关系。方法 对 3 0例急性脑梗死患者和 40例健康人血清血管内皮生长因子含量进行测定。患者采血时间为病后第 2天或第 3、4天 ,取均数与对照组比较。结果 3 0例急性脑梗死患者血清 VEGF含量为 (2 95 .0 4± 3 5 .73 ) pg/ ml,对照组为 (13 7.71± 11.5 3 ) pg/ m l,两组比较差异显著。结论 急性脑梗死患者血清 VEGF升高 ,提示 VEGF是脑梗死急性期的自我保护机制之一。
Objective To explore the levels of serum vascular endothelial growth factor(VEGF) in the 30 patients with acute cerebral infarction. Methods Two ml of blood was collected 2d or 3d or 4d after seizures from each of patients with acute cerebral infarction. Also two ml of blood was drawn from each of the normal control group. After centrifugation,the samples were stored -70℃ until analysis. The level of VEGF after seizures were compared with the controls. Results The levels of serum VEGF in the patients were (295.04±35.73)pg/ml,the levels of serum VEGF in controls were (137.71±11.53)pg/ml. The levels of serum VEGF in the patients were significantly higher than in the normal controls. Conclusion The serum VEGF could be induced to reach higher levels in the acute cerebral infarction patients,which suggested VEGF is one of the protected factors in the acute period of cerebral infarction.
出处
《中风与神经疾病杂志》
CAS
CSCD
北大核心
2003年第1期61-62,共2页
Journal of Apoplexy and Nervous Diseases
关键词
急性脑梗死
血清
血管内皮生长因子
测定
Acute cerebral infarction
Vascular endothelial growth factor(VEGF)
