摘要
赭曲霉毒素A(OA)主要由纯绿青霉、赭曲霉和碳黑曲霉产生 ,主要污染谷物、动物饲料和动物性食品 (猪肾脏、肝脏 ) ,是具有很强力的肝脏毒性和肾脏毒性 ,并有致畸、致突变和致癌作用的一种真菌毒素 ;在世界某些地区 ,该毒素被怀疑与猪真菌毒素肾病有关 ,并在流行区人血液中检出该毒素。膳食摄入OA与人类健康的关系越来越引起人们的重视 ,本文就OA产生菌、对农作物的污染。
Ochratoxin A (OA) is produced mainly by Penicillium verrucosum, Aspergillus ochraceus and A. carbonarius and it was found as a contaminant in the large number of agricultural commodities, feedstuffs and animal organs such as kidney and liver of pig. Toxicological studies indicated that OA is a teratogenic, mutagenic and carcinogenic mycotoxin with the strong toxic effects on liver and kidney. In some endemic areas in the world, OA was suspected to be related to swine nephropathy and has been detected in blood samples from inhabitants in these areas as well. More and more attention was paid to the relationship between the consumption of food contaminated with OA and human health. In this paper, OA-producing fungi, the contamination of it to the agricultural commodities, its toxicity and risk assessment are reviewed.
出处
《卫生研究》
CAS
CSCD
北大核心
2003年第2期172-175,共4页
Journal of Hygiene Research
基金
国家"十五"科技攻关重大项目 (No .2 0 0 1BA80 4A0 2 )
关键词
赭曲霉毒素A
污染
毒性
健康
Ochratoxin A, natural occurrence, toxicity, human health
