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恶性肿瘤放化疗并发带状疱疹的临床分析 被引量:21

Clinical analysis of radio-chemotherapy for malignant tumor complicated with herpes zoster
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摘要 目的探讨恶性肿瘤放化疗并发带状疱疹治疗的疗效及临床意义。方法 回顾性分析1984.年1月~2001年8月的68例恶性肿瘤放化疗并发带状疱疹的临床资料、治疗方法、随访结果及生存情况做分析研究。结果全组1、3、5年生存率分别为45.6%、26.5%和23.4%。其中局限型1、3、5年生存率为45.2%、41.9%和35.5%;播散型1、3、5年生存率为13.5%、5.4%和5.4%。两者比较有非常显著性差异(P<0.01)。全组死亡39例(57.4%),其中1年内死亡37例(54-4%),半年内死亡26例(38.2%)。结论 对恶性肿瘤放化疗并发带状疱疹应有足够的认识,以期早期发现、早期诊断、早期治疗,减少不必要的并发症的发生是提高患者生活质量及延长生存期的关键。 Objective To study the curative effect of radio-chemotherapy for tumors complicated with herpes zoster and its clinic signifiance. Methods A retrospective study was conducted on 68 malignant tumor patients complicated with zoster treated bg radio-chemotherapy admitted from January 1984 to August 2001 with emphasis on clinical data, treatment, follow-up results and survival. Results The overall 1-, 3- and 5-year survival rates were 45.6% , 26.5% and 23.4% respectively. The 1-, 3- and 5-year survival rates of the localized type were 45.2%, 41.9% and 35.5% respectively. Meanwhile the 1-, 3- and 5-year survival rates of the diffuse type were 13.5%, 5.4% and 5.4% respectively (P<0.01). Follow-up showed that 39(57.4%) patients were dead; 37(54.4%) patients died within one year; 26(38.2%) patients died within six months. Conclusion More attention must be paid in clinical parctice and correct diagnosis should be made as early as posisble to avoid unpredictable comlications.This is the key point to improve patient life guality and survival time.
出处 《肿瘤》 CAS CSCD 北大核心 2003年第1期71-72,共2页 Tumor
关键词 恶性肿瘤 带状疱疹 临床分析 并发症 化学疗法 放射疗法 Malignant tumor Radio-chemotherapy Herpes zoster Clinical analysis
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