摘要
正常妇女的绝经年龄与月经初潮年龄、人种、孕产状态、营养、遗传及其他社会环境因素可能都有关系。据调查,我国妇女的绝经年龄一般在45～50岁。北美妇女绝经年龄平均约50岁。卵巢早衰,指的是妇女有正常的月经初潮,并持续一段时间内正常行经,但在35岁或认为40岁以前过早地绝经。这些妇女常伴有不育,潮热,高血促性腺激素而低雌素水平,其卵巢活检看不见滤泡。我院1983～1984年遇4例卵巢早衰患者,经腹部小切口取出少量卵巢组织,与绝经后及育龄期卵巢对照,行光镜及电镜观察,结果报导如下。
This article reported the clinical,endocrinological and ovarian histological features of POF in 4 cases. The clinical charecteristics were:Age of menarche and secondary charecteristics are normal, without galactorrhea;Regular menstrual periods for several years before the amenorrhea at ages of 20 to 22 with vasomotor symptoms and infertility;Normal genitalia or sinile vaginitis and mild degree of uterine atrophy found on gynecologic exam;No case was complicated with autoimmune disorders;chromosomes were all 46;ⅩⅩ. Vaginal smear revealed lowered estrogenic effects;amount of serum gonadotrophin increased, both ovaries were small.No follicles but dense mesenchyme,scanty vascularity,hyalinization of bl- ood vessels were found on light microscopy.There were abundant amount of collagen fibers under the electronic microscopy.
出处
《解放军医学院学报》
CAS
1987年第2期159-161,190,共4页
Academic Journal of Chinese PLA Medical School
