摘要
This paper presents our successful one-step preparation of the spherical crossIinked polyvinyl alcohol (PVA) carrier directly from PVA with terephthalic aldehyde (TPA) as crosslinking agent. The obtained hydrophilic carrier was then reacted with p-(β-sulfato-ethylsulfonyl)-aniline (SESA) through etherification to give a reactive polymer, which was further coupled with trypsin.