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血管内皮生长因子和皮肤肿瘤

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摘要 血管内皮生长因子是一高度特异的血管内皮细胞有丝分裂原 ,最重要的促血管生长因子之一 ,调节生理性和病理性血管生成。血管内皮生长因子受体特异性地分布于血管内皮细胞表面 ,具有酪氨酸激酶活性。血管内皮生长因子及其受体在皮肤肿瘤中表达 ,并与皮肤肿瘤的发生、发展、转移以及判断皮肤肿瘤的良恶性有关 。
作者 李芃 涂亚庭
出处 《国外医学(皮肤性病学分册)》 2003年第2期97-99,共3页 Foreign Medical Sciences(Section of Dermatology and Venereology)
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  • 1Dvorak HF, Brown LF, Detmar M, et al. Vascular permeability fac tor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am J Pathol, 1995, 146(5) :1029 -1039. 被引量:1
  • 2Ruckman J, Green LS, Beeson J, et al. 2'- Fluoropyrimidine RNAbased aptamers to the 165 - amino acid form of vascular endothelial growth factor ( VEGF165 ). Inhibition of receptor binding and VEGFinduced vascular permeability through interactions requiring the exon 7 - encoded domain. J Biol Chem, 1998, 273 (32) :20556 - 20567. 被引量:1
  • 3Shen BQ, Lee DY, Gerber HP, et al. Homologous up-regulation of KDR/Flk-1 receptor expression by vascular endothelial growth factor in vitro. J Biol Chem, 1998, 273(45) :29979 -29985. 被引量:1
  • 4Szabo S, Sandor Z. The diagnostic and prognostic value of tumor angiogenesis. Eur J Surg Suppl, 1998, (582) :99 - 103. 被引量:1
  • 5Marti HH, Risan W. Systemic hypoxia changes the organ-specific distribution of vascular endothelial growth factor and its receptors. Proc Natl Acad Sci U S A, 1998, 95(26) :15809 -15814. 被引量:1
  • 6Akiri G,Nahari D, Finkelstein Y, et al. Regulation of vascular endo thelial growth factor (VEGF) expression is mediated by internal initiation of translation and alternative initiation of transcription. Onco gene, 1998, 17(2):227-236. 被引量:1
  • 7Raleigh JA, Catkins-Adams DP, Rinker LH, et al. Hypoxia and vas cular endothelial growth factor expression in human squamous cell carcinomas using pimonidazole as a hypoxia marker. Cancer Res, 1998, 58(17) :3765 -3768. 被引量:1
  • 8Rak J, Yu JL, Klement G, et al. Oncogenes and angiogenesis: signa ling three-dimensional tumor growth. J Investig Dermatol Symp Proc, 2000, 5(1) :24 -33. 被引量:1
  • 9Tsao MS, Liu N, Nicklee T, et al. Angiogenesis correlates with vas cular endothelial growth factor expression but not with Ki-ras oncogene activation in non-small cell lung carcinoma. Clin Cancer Res, 1997, 3(10) :1807 -1814. 被引量:1
  • 10Giatromanolaki A, Koukourakis MI, Kakolyris S, et al. Vascular en dothelial growth factor, wild-type p53, and angiogenesis in early operable non-small cell lung cancer. Clin Cancer Res, 1998, 4 ( 12 ): 3017 - 3024. 被引量:1

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