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二甲双胍联合克罗米芬对多囊卵巢综合征合并不孕症疗效分析

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摘要 目的:探讨二甲双胍、克罗米芬联合治疗多囊卵巢综合征(polyCySTiC ovarian Syndrome,pCoS)合并不孕症的临床疗效情况。方法:根据治疗方案不同将我院80例pCoS合并不孕症患者分为观察组40例(应用二甲双胍、克罗米芬治疗)及对照组40例(应用克罗米芬单药治疗)。治疗3个月经周期后,对比两组激素水平变化情况,并统计患者半年妊娠率。结果:治疗后,观察组促卵泡雌激素、促黄体生成素、睾酮及空腹胰岛素水平均显著低于对照组(p<0.05)。随访发现,观察组半年妊娠率为37.50%,明显高于对照组15.00%(p<0.05)。结论:采用二甲双胍、克罗米芬联合治疗pCoS合并不孕症可有效改善患者激素水平、提高患者妊娠率。
作者 周志敏
出处 《健康之路》 2016年第3期81-82,共2页 Health Way
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  • 1Rotterdam ESHRE/ASRM -Sponsored PCOS Consensus Work- shop Group. Revised 2003 consensus on diagnostic criteria and long- term health risks related to polycystic ovary syndrome [J].Fertil Steril, 2004, 81 (1): 19. 被引量:1
  • 2De Leo V, Musacchio MC, Palermo Vet al. Polycystic ovary syndrome and metabolic comorbidities: therapeutic options [J]. Drugs Today (Barc), 2009 , 45 (10) : 763. 被引量:1
  • 3Fusco A, Bianchi A, Mancini A et al. Effects of ghrelin admin-istration on endocrine and metabolic parameters in obese women with polycystic ovary syndrome [J]. J Endocrinol Invest, 2007, 30 (11): 948. 被引量:1
  • 4Teede HJ, Meyer C, Hutchison SK et al. Endothelial function and insulin resistance in polyeystie ovary syndrome: the effects of medical therapy [J]. Fertil Steril, 2010, 93 (1) : 184. 被引量:1
  • 5Tan S, Hahn S, Benson Set al. Metformin improves polycystic ovary syndrome symptoms irrespective of pre - treatment insulin resistance [J]. Eur J Endocrinol, 2007 , 157 (5) : 669. 被引量:1
  • 6He D, Jiang F. Meta - analysis of letrozole versus clomiphene citrate in polycystie ovary syndrome [J]. Reprod Biomed Online, 2011, 23 (1): 91. 被引量:1
  • 7Zhang X J,Huang L L,Su H X,et al.Characterizing plasma phospholipid fatty acid profiles of polycystic ovary syndrome patients with and without insulin resistance using GC–MS and chemometrics approach[J].J Pharmaceutical Biomedical Analysis,2014,95:85-92. 被引量:1
  • 8Weintraub A,Margalioth E J,Chetrit A B,et al.The dynamics of serum anti-Mullerian-hormone levels during controlled ovarian hyperstimulation with GnRH- antagonist short protocol in polycystic ovary syndrome and low responders[J].Eur J Obstet Gynecol Reprod Biol,2014,176:163-167. 被引量:1
  • 9Raja-Khan N,Kunselman A R,Hogeman C S,et al.Effects of atorvastatin on vascular function,inflammation,and androgens in women with polycystic ovary syndrome:a double-blind,randomized,placebo- controlled trial[J].Fertil Steril,2011,95(5):1849-1852. 被引量:1
  • 10Takahashi T,Igarashi H,Hara S,et al.Brachial-to-ankle pulse wave velocity as an independent prognostic factor for ovulatory response to clomiphene citrate in women with polycystic ovary syndrome[J].J Ovarian Res,2014,7:74. 被引量:1

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