摘要
目的:评估市场主流安全套的生物毒性。方法:在安全套中加入1.0ml精子应用液,振荡3min后取出,观察油滴的数量,分别在5、60min检测精子活动率,同时与精子应用液的精子活动率进行对比。结果:安全套与精子接触5min,23种型号安全套中有18种的精子存活指数<0.80;接触60min,23种安全套的精子存活率均<0.80;安全套的油滴随着时间延长逐渐减少或消失。结论:16个品牌的23种安全套均具有精子生物毒性,毒性强弱与安全套的品牌、型号及接触时间相关;用于人类辅助生殖技术(ART)相关检查或治疗所需的安全套,应该选择未添加杀精剂和无油的产品,并进行精子毒性试验筛查,选用低精子生物毒性的安全套。
Objective:To evaluationthe of the biotoxicity on sperm of condom in the market mainstream.Methods:1.0 ml sperm application liquid was added into the condom,and the number of oil droplets was counted after 3 minutes of oscillation.The sperm motility rate was measured after 5 minutes and 60 minutes respectively,and the sperm motility rate was compared with sperm in sperm application liquid non-contacted the condoms during the same time.Results:The sperm survival index of 18 in these 23 models condoms was less than 0.8 after 5 minutes of sperm contacted condom,and the sperm survival rate of these 23 models condoms was less than 0.8 after 60 minutes of sperm contacted condom.The number of oil droplets of condoms had gradually decreased or disappeared over time.Conclusion:23 models condoms from 16 brands all have sperm toxicity,and the toxicity degree is related to the brand,condoms model,and time of sperm contacting condoms.When condoms used for human assisted reproductive technology(ART),it should be chosen condoms with no spermicide and oil-free,and sperm biotoxicity test of condom is necessary for help to choose the condom with low sperm biotoxicity.
作者
胡晓薇
朱卫中
周慧敏
赵恩慧
叶明建
李金美
HU Xiaowei;ZHU Weizhong;ZHOU Huimin;ZHAO Enhui;YE Mingjian;LI Jinmei(Lishui People’s Hospital,Zhejiang Province,323000)
出处
《中国计划生育学杂志》
2019年第6期691-694,共4页
Chinese Journal of Family Planning
