摘要
以对甲苯氰为原料,经光氯化,Holfmann氮化反应合成了对氰基苄胺,并对产物进行了分析表征。在优化条件下,产物的总收率为60%,含量99.2%(HPLC)。
In this article, the method of preparation for 4-cyanobenzylamine was briefly reviewed and. starting from 4-cyanotoluene, it was synthesized by photochlori-nation followed by Holftnann amination. The product was identified by IR, 1HNMR, etc. By optimization, the yield and purity reached to 60% and 99. 2% respectively.
出处
《化学试剂》
CAS
CSCD
北大核心
2003年第1期53-54,共2页
Chemical Reagents
基金
湖南省教育厅资助项目(010066)。