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原发性肝细胞癌86例行不规则切除疗效分析

Effect of irregular hepatectomy for primary hepatocellular carcinoma
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摘要 目的 :评价不规则切除术治疗原发性肝细胞癌 ( PHCC)的疗效。方法 :行不规则切除术治疗 PHCC86例。结果 :全组手术死亡 1例 ,1、3年生存率为 6 5例 ( 75 .6 % ) ,5 3例 ( 6 1.6 % )。 <3cm、3~ 5 cm、>5 cm的 1、3年生存率分别为 18例 ( 90 .0 % ) ,16例 ( 80 .0 % ) ,2 1例 ( 75 .0 % ) ,19例 ( 6 7.9% ) ;2 5例 ( 6 5 .8% ) ,18例 ( 4 7.4 % )。单纯手术组和手术加行肝动脉灌注 ( HAI)和门静脉灌注组 ( PVI)的 1、3年生存率分别为 72 .1%、6 0 .7% ,84 .0 %、6 8.0 %。结论 :采用不规则切除术对机体创伤小 ,减少了术后并发症的发生 ,其临床疗效与规则性肝切除相仿。对大肝癌不要轻易放弃手术 。 Objective:To evaluate the effect of irregular hepatectomy for primary hepatocellular carcinoma.Methods:Clinical data on 86 patients who undergone irregular hepatectomy were reviewed retrospectively.Results:The mortality of hepatectomy was 1 case,The overall 1- and 3-year survival rates were 75.6% and 61.6%, respectively . The 1- and 3-year survival rates in patients whose tumor size was less than 3 cm in diameter,between 3-5 cm and more than 5 cm were 90.0 %,80.0 %,75.0% 67.9 %,65.8 % 47.4 %, respectively. In the patients who received irregular hepatectomy only and incidental HAI and/or PVI, The 1- and 3-year survival rates were 72.1% 60.7%,84.0% 68.0 %, respectively. Conclusion:Irregular hepatectomy cause little damage to the body, reduces postoperative complication and has a good prognosis.It can also be used to big hepatocellular carcinoma, big hepatocellular carcinoma should be treated actively. The supplement therapy should be improved.
出处 《南通医学院学报》 2003年第1期60-61,共2页 ACTA Academiae Medicinae Nantong
关键词 原发性肝细胞癌 不规则肝切除术 疗效 Primary hepatocellular carcinoma Irregular hepatectomy
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