摘要
目的 研究IVF ET早期自然流产的发生率及其发生的相关因素。方法 1998年 12月 1日至 1999年 9月2 5日在本中心行IVF ET获得妊娠的患者 ,根据其妊娠结局分为流产组和分娩组 ,并回顾性比较分析她们的年龄 ,流产史 ,支、衣原体感染史 ,男方少弱精行ICSI操作史 ,月经第三天的基础激素水平 ,促性腺激素开始注射日的FSH、LH、E2水平 ,HCG注射日的FSH、LH、E2、P的水平 ,以及取卵日的子宫内膜厚度 ,子宫大小和ET的胚胎评分等。结果 本中心IVF ET的流产率为 2 6 % ,IVF ET的流产多为早期自然流产 (6 5 .38% ) ,流产组与分娩组的流产史 ,基础雌激素水平 ,第三天移植胚胎的CES/移植胚胎数有显著性差异 ,而两组的年龄 ,支、衣原体感染史 ,ICSI操作 ,基础FSH、LH、P、T ,促性腺激素开始注射日的FSH、LH、E2水平 ,HCG注射日的FSH、LH、E2、P的水平 ,以及取卵日的子宫内膜厚度 ,子宫大小均无显著性差异。结论 IVF ET的流产多为早期自然流产 ,且与患者的基础雌激素水平及第三天胚胎的形态学评分有关。此外 ,还与患者的流产史有关。
Object: To investigate the rate and correlation factors of early spontaneous abortion in IVF?ET. Methods: Calculated the IVF?ET patient between November 1998 to September 1999, then divided all pregnancy patient into abortion group and delivery group. And analyses their age, abortion history, CT/TT infection, ICSI program, endocrine hormone on day 3, ignition day, and HCG administration day, uterus size, thick of endometrium on oocyte pickup day, score of ET embryo. Result: the rate of early spontaneous abortion in IVF?ET is 26%. About 65.38% pregenancy loss in IVF?ET is early spontaneous abortion. The abortion history and E2 level on day 3 of mense cycle have significant difference in abortion group and delivery group. But have no difference in age, cycle day 3 FSH, LH, P, T level, FSH, LH, E2 level on inanition day, FSH, LH, E2, P level on HCG administration day, number of retrieved oocytes, abortion group and delivery group. Conclusion: About 65.38% pregenancy loss in IVF?ET is early spontaneous abortion. The factors in early spontaneous abortion in IVF?ET may be have something to do with the abnormal of endometrium reception. And the factors causing abortion can not be treated by IVF?ET.
出处
《中国优生与遗传杂志》
2003年第1期66-67,80,共3页
Chinese Journal of Birth Health & Heredity
