摘要
目的 研究冠心病 (CHD)患者血浆同型半胱氨酸 (HCY)水平与健康人的差异。方法 采用荧光偏振免疫法 (FPIA) ,对2 5例CHD患者和 2 0例对照者进行血浆HCY浓度测定 ,并对测定结果进行统计学处理、分析。结果 CHD患者的HCY水平高于对照组 ,且具有显著性差异 (P <0 .0 0 1 )。结论 临床应监测并控制CHD患者的HCY血浆浓度 ,并对高HCY血症患者给予相应的治疗 。
OBJECTIVE: To study the difference of plasma homocysteine(HCY) concentrations between coronary heart disease (CHD) patients and healthy volunteers. To determine whether creatinine levels affect plasma HCY concentrations. METHODS: 25 CHD patients and 20 healthy volunteers were enrolled. The plasma concentrations of HCY were determined by fluorescence polarization immunoassay(FPIA). RESULTS: Compared with the healthy group, the concentrations of HCY in CHD group were higher, and the differences were statistically significant(P < 0.001). CONCLUSIONS: It strongly suggested to monitor and control the plasma concentrations of HCY in patients with CHD, and corresponding treatment should be given to hyperhomocysteine patients.
出处
《中国药学杂志》
EI
CAS
CSCD
北大核心
2003年第1期47-49,共3页
Chinese Pharmaceutical Journal
