摘要
目的 总结膀胱引流式胰、肾联合移植术后长期存活患者代谢性酸中毒的演变规律及处理经验。方法 对 2例膀胱引流式胰、肾联合移植术后长期存活 (5年 ,8年 )患者进行随访 ,观察其临床表现、血液气体分析及碳酸氢钠的给药方式、剂量和疗效。结果 2例患者术后均发生代谢性酸中毒 ,需长期给予碳酸氢钠替代治疗。结论 膀胱引流式胰、肾联合移植术后的代谢性酸中毒很难自行代偿纠正 。
Objective To sum up the progression law and the treatment experience of metabolic acidosis in long term survival patients with simultaneous pancreas and kidney transplantation (SPK). Methods Two cases with survival time of 6~8 years after SPK were followed up. The clinical manifestations , changes in blood gas and the pattern and dose of sodium bicarbonate administration were observed. Results Metabolic acidosis occurred in both of two cases after transplantation. Sodium bicarbonate replacement was permanently necessary for the patients although the drug dose could be diminished gradually.Conclusion Metabolic acidosis is a long term and boring complication which is difficulty to recover completely by self adjustment in the long term survival patients with SPK. It is a main factor to influence life quality of the patients. The conversion from bladder drainage to enteric drainage of pancreas juice may be an ultimate solution.
出处
《中华器官移植杂志》
CAS
CSCD
北大核心
2003年第1期39-40,共2页
Chinese Journal of Organ Transplantation
关键词
代谢性酸中毒
术后并发症
肾移植
胰腺移植
Pancreas
Kidney
Organ transplantation
Acidosis
Postoperative complications