期刊文献+

立体定向放射治疗照射野剂量分布特点及应用 被引量:5

Charateristic of dose distribution and its clinical application in stereotactic radiotherapy practice
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摘要 目的:测量目前广泛应用的立体定向放射治疗系统(SRT—X刀)准直器射野的临床剂量学参数,探索正确的临床使用方法。材料与方法:用组织等效固体水模、仿真人体头模和胶片剂量测量系统测量BrainLAB X刀系统在静态、单靶(中心)旋转、两靶旋转照射时的离轴比、半影、锐度、平坦度等剂量学参数。结论:了解和掌握不同照射技术时,X刀准直器射野剂量学参数的变化是正确使用立体定向放射治疗技术的一个关键因素,特别是在鼻咽癌的多靶点补量治疗时尤为重要。本文提出了临床使用时的一些具体建议。 Purpose: To measure clinical dosimetric parameters and to evaluate the accuracy of isocenter dose distribution in circular collimater fields in stereotactic radiotherapy for correctly using of stereotactic radiotherapy in clinical practice. Materials and Methods: Polystyrene phantom, Anthropomorphic head phantom and film-checking technique were used to measure the parameters of off-axis ratio, penumbra, steepness and flatness of isodose curves under static, single-target, and 2-targets-isocenters moving fields condition in BrainLAB X-knife system. Conclusion: Our parameters obtained from above-mentioned different measurement methods demonstrated that to understand thoroughly the variations of clinical dosimetric parameters at the isocenter of circular collimeter fields is one of the key factors for performing correctly the stereotactic radiotherapy techniques in clinical practice, such as, when you choose multi-targets X-knife therapy method for the nasopharyngael carcinoma. Some suggestions were offered according to the results of our test measurements for guiding the correct application of stereotactic radiotherapy in clinical practice.
出处 《中国医学物理学杂志》 CSCD 2003年第1期9-12,共4页 Chinese Journal of Medical Physics
基金 四川省卫生厅重点科研项目
关键词 立体定向放射治疗 仿真体模 胶片剂量学 鼻咽癌 stereotactic radiotherapy anthropomorphic phantom film dosimetry nasopharyngeal carcinoma
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参考文献2

  • 1胡逸民主编..肿瘤放射物理学[M].北京:原子能出版社,1999:659.
  • 2冯宁远等编著..实用放射治疗物理学[M],1998:443.

同被引文献43

  • 1马永忠,王时进,苏旭.立体定向放射治疗系统定位精度的测量与分析[J].中国卫生工程学,2005,4(6):367-370. 被引量:4
  • 2马永忠,王时进,苏旭.立体定向放射治疗中靶外剂量分布的研究[J].中国职业医学,2006,33(2):94-97. 被引量:3
  • 3伏少华,张可领,肖作平,刘永明.立体定向放射外科加速器等中心机械误差的测量[J].功能性和立体定向神经外科杂志,1996,9(4):23-24. 被引量:2
  • 4[7]Maruyama,Mylrea MM,Logothetis J,Nearopathy following irradiation.An unusual late complication of radiontherapy[J].Am J Roentgenol Radium Ther Nucl Med,1967,101(1):216~9. 被引量:1
  • 5[3]Lin YS,Jeu YM,Lin JC.Radiation-induced cranial never palsy in patient with nasopharyngeal carcinoma[J].Cancer,2002,95(2):404~13. 被引量:1
  • 6[6]Emami B,Lyman J,Brown A,et al.Tolerance of normal tissue to therapentic irracliation[J].Int J Radiat Oncol Biol Phys,1991,21(1):109~22. 被引量:1
  • 7Chua D T, Sham J S, Huang K N, et al. Stereotactic mdiosurgery as a salvage treatment for locally persistent and recurrent nasopharyngeal carcinoma [J]. Head Neck, 1999, 21 (7): 620-626. 被引量:1
  • 8Hotmes T W, Hudes R, Dziuba S, et al. Stereotaetie image-guided intensity modulated radiotherapy using the HI-ART Ⅱ helical tomother- apy system [J]. Medical dosimetry, 2008, 33 (2): 302-308. 被引量:1
  • 9Jin J Y, Ryu S, Faber K, et al. 2D/3D image fusion for accurate target localization and evaluation of a mask based stereotactic system in fractionated stereotactic radiotherapy of cranial lesions [ J ]. Medical Physics, 2006, 33 (12): 4557-4565. 被引量:1
  • 10Hoffmann L. Implementation and experimental validation of the high dose rate stereotactic treatment mode at Varian accelerators [ J]. Acta Oncologica, 2009, 48 (2): 201-208. 被引量:1

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