摘要
目的分析研究银杏达莫联合依达拉奉治疗急性脑梗塞的临床疗效及安全性。方法整群选取于2014年1月—2015年5月来院治疗的急性脑梗塞患者79例作为研究对象,按治疗方法的不同分为对照组(n=38)和观察组(n=41),对照组给予单纯依达拉奉治疗,观察组给予银杏达莫联合依达拉奉治疗,采用美国国立卫生研究院卒中量表(NIHSS)对患者的各项指标进行评定,观察对比两组患者的临床效果及不良反应发生情况。结果观察组的有效率为95.12%,对照组的有效率为78.95%,差异有统计学意义(P<0.05);观察组治疗后的神经功能缺损评分为(13.43±2.03)分,优于对照组的(17.89±3.27)分,差异有统计学意义(P<0.05);观察组的不良反应发生率(7.32%)略低于对照组(13.16%),差异无统计学意义(P>0.05)。结论急性脑梗塞采取银杏达莫联合依达拉奉治疗的临床效果优于单纯依达拉奉治疗,且安全性好,值得在临床中推广使用。
Objective To analyze clinical effect and safety of Yinxingdamo injection combined with edaravone in treatment of acute cerebral infarction. Methods A total of on 5 January 2014 to 2015 to hospital treatment of patients with acute cerebral infarction in 79 cases as the research object, according to the different treatment methods as control group(38 cases) and observation group(n=41), the control group was treated with edaravone treatment, observation group give ginkgo leaf extract and dipyridamole injection combined with edaravone, by the United States National Institutes of Health Stroke Scale(NIHSS) for patients with various indicators of evaluation, to observe the clinical effects and side effects were compared between the two groups occurred. Results In the observation group, the efficiency was 95.12%. In the control group effective 78.95%, the difference was statistically significant(P<0.05); neurological function deficit scores were observed after the treatment group for(13.43 ±2.03), which was significantly better than that of the control group(17.89±3.27) and the difference was statistically significant(P<0.05). In the observation group,the adverse reaction occurrence rate(7.32%) is slightly lower than that of the control group(13.16%), but the difference was not significant(P>0.05). Conclusion Acute cerebral infarction by edaravone combined with ginkgo leaf extract and dipyridamole in the treatment of clinical effect is better than pure edaravone treatment and safety of good, it is worth in clinical application.
出处
《中外医疗》
2015年第28期158-160,共3页
China & Foreign Medical Treatment
关键词
急性脑梗塞
银杏达莫
依达拉奉
安全性
Acute cerebral infarction
Ginkgo dipyridamole
Edaravone
Safety
