摘要
目的分析D-二聚体阴性下肢深静脉血栓患者临床特征。方法选取D-二聚体阴性且确诊为下肢深静脉血栓的患者103例为观察组,另取同期于郑州大学第一附属医院就诊的D-二聚体阴性且排除下肢深静脉血栓的患者103例为对照组,观察比较两组患者的临床特征。结果观察组出现下肢疼痛及水肿的比例显著高于对照组(P<0.05);观察组血栓主要分布在小腿肌间静脉;观察组出现外伤、外科手术、恶性肿瘤、恶性肿瘤静脉内化疗及长期制动的比例显著高于对照组(P均<0.05)。结论虽然D-二聚体阴性是排除下肢深静脉血栓形成的有效方法;但当患者有恶性肿瘤、外伤、外科手术、恶性肿瘤静脉内化疗或长期制动病史,且出现下肢疼痛、水肿的症状体征时,即使D-二聚体阴性,亦应警惕下肢深静脉血栓形成。
Objective To analyze the clinical features of D-dimer negative deep venous thrombosis of lower extremities.Methods Tatolly 103 cases of D-dimer negative deep venous thrombosis of lower extremities were selected as observation group;103 cases of D-dimer negative without deep venous thrombosis of lower extremities were selected as control group.And we analyzed the clinical of the two groups.Results The incidence of lower limb pain and edema in the observation group was significantly higher than that in the control group(P<0.05).The thrombus in the observation group was mainly distributed in the intermuscular vein of the calf.The proportion of trauma,surgical operation,malignant tumor,intravenous chemotherapy and long-term immobilization in the observation group was significantly higher than that in the control group(P<0.05).Conclusion Although the negative D-dimer is an effective method for the elimination of deep venous thrombosis of the lower extremities,the patients with malignant tumor,trauma,surgery or intravenous chemotherapy should be alert to the formation of deep venous thrombosis of the lower extremities even if the D-dimer is negative,especially when the have symptoms and signs of lower limb pain and edema.
作者
张艳
冯宁
杜方雪
高硕辰
杨颍
ZHNAG Yan;FENG Ning;DU Fang-xue;GAO Shuo-chen;YANG Ying(The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)
出处
《医药论坛杂志》
2019年第8期4-6,共3页
Journal of Medical Forum
基金
河南省医学科技攻关计划项目(201602066)
河南省科技厅社会发展攻关项目(172102310048)
关键词
D-二聚体阴性
下肢深静脉血栓
诊断
临床特征
D-dimer negative
Thrombosis of lower extremities
Diagnosis clinical feature
