摘要
目的:比较分析单纯经尿道切除术、经尿道切除术+术后吡柔比星灌注治疗腺性膀胱炎的临床疗效。方法:以2013年1月~2015年6月收治的50例腺性膀胱炎患者为研究对象,其中行经尿道切除术+术后吡柔比星灌注治疗28例,计为观察组,单纯经尿道切除术治疗的22例,计为对照组,比较两组临床疗效、并发症、治疗前后尿动力学指标及术后1年生活质量情况。结果:术后1年两组治疗总有效率比较差异无统计学意义,但观察组1年复发率3.57%,显著低于对照组的22.73%;与治疗前比较,两组治疗后最大尿流率、平均尿流率均显著提高,最大尿道压显著下降,差异有统计学意义,且观察组治疗后上述指标均明显优于对照组;两组膀胱刺激征、尿道狭窄及血尿发生率比较无显著差异。术后1年观察组躯体功能评分、心理功能评分分别为(74.72±7.16)分、(70.20±9.15)分,较对照组的(70.00±8.47)分、(75.94±8.72)分,差异有统计学意义。结论:单纯经尿道切除术与经尿道切除术+术后吡柔比星灌注治疗腺性膀胱炎1年疗效类似,但后者对患者尿动力学改善更明显,1年复发率显著低。
Objective To compare clinical efficacy of simple transurethral resection and combination of transurethral resection and postoperative pirarubicin instillation in the treatment of cystitis glandularis. Methods 50 patients with cystitis glandularis from January 2013 to June 2015 treated in our hospital were selected as the research objects, 28 patients who received transurethral resection surgery+postoperative pirarubicin instillation were marked as the observation group, 22 patients who received simple transurethral resection surgery were marked as the control group, clinical efficacy, complications, urinary dynamics indexes before and after the treatment, postoperative 1 year quality of life between the two groups were compared. ResultsThere was no significant difference in total effective rate of the two groups 1 year after the operation, but 1 year recurrence rate of the observation group 3.57% was significantly lower than the control group(22.73%); compared with those before the treatment, maximum urinary flow rate, average urinary flow rate in the two groups after the treatment were significantly increased, maximal urethral pressure was significantly decreased, above indexes in the observation group after the treatment were significantly better than the control group; there was no significant difference in incidence of irritation sign of bladder, urethral stricture, hematuresis in the two groups. There was a significant difference in somatic function score, mental function score in the observation group [(74.72±7.16) score,(70.20±9.15) score] and the control group [(70.00±8.47) score,(75.94±8.72) score] 1 year after the operation. Conclusion Efficacy of simple transurethral resection and combination of transurethral resection and postoperative pirarubicin instillation in the treatment of cystitis glandularis is similar, but the latter can improve urinary dynamics of patients more apparently with significantly low 1 year recurrence rate.
出处
《湖南师范大学学报（医学版）》
2017年第5期95-97,共3页
Journal of Hunan Normal University(Medical Sciences)
关键词
腺性膀胱炎
经尿道切除术
吡柔比星灌注
临床疗效
cystitis glandularis
transurethral resection
pirarubicin instillation
clinical efficacy
