摘要
目的:初步探讨体质指数(BMI)和生长激素释放肽(ghrelin)对于预测急性胰腺炎严重程度的价值。方法:收集确诊的急性胰腺炎患者76例,用酶联免疫吸附实验方法测定急性胰腺炎患者入院和治疗2周后的血清ghrelin、TNF-α和IL-1β水平。结果:本研究中发现重症胰腺炎(SAP)组患者的BMI和入院时ghrelin、TNF-α和IL-1β水平要显著高于轻症急性胰腺炎(MAP)组和对照组,治疗2周后MAP和SAP组的ghrelin、TNF-α和IL-1β水平出现下降。结论:血清ghrelin和BMI可以做为预判急性胰腺炎病情严重程度的指标之一,ghrelin的升高与急性胰腺炎的严重程度有关。
Objective Discuss the Predict and Prognosis of BMI or ghrelin to predict severity degree in acute pancreatitis patients. Methods 76 patients with acute pancreatitis were internalized in our research. The blood was collected in admission and after two weeks treatment,ELISA was used to test the serum levels of ghrelin、TNF-α and IL-1β. Results Compared with MAP and control groups,BMI and the serum levels of ghrelin,TNF-α and IL-1β in admission were increased in SAP group( P < 0. 05). The serum levels of ghrelin、TNF-α and IL-1β were decreased in MAP and SAP groups after 2 weeks treatment. Conclusion The serum levels of ghrelin and BMI have the close relationship to predict the severity of acute pancreatitis. The increase of ghrelin levels in serum have relationship to the severity of acute pancreatitis.
出处
《湖南师范大学学报（医学版）》
2014年第1期53-55,共3页
Journal of Hunan Normal University(Medical Sciences)
