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颅内血肿微创清除术联合亚低温治疗高血压脑出血的临床疗效研究 被引量:14

The clinical efficacy research of micro-invasive evacuation of intracranial hematoma combined with mild hypothermia therapy in hypertensive cerebral hemorrhage patients
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摘要 目的探讨颅内血肿微创清除术联合亚低温治疗高血压脑出血的临床疗效。方法将符合标准的51例高血压脑出血患者,随机分成观察组(26例)和对照组(25例),观察组使用微创清除术联合亚低温进行治疗,对照组使用单独微创清除术进行治疗。比较2组患者治疗后的疗效及格拉斯哥(GCS)评分神经功能缺损(CSS)程度评分。结果观察组治愈率与总有效率分别为23.1%,88.5%,均显著性高于对照组的4.0%,48.0%(P<0.05)。术后7d与14d观察组GCS评分为6.77±1.80与9.38±2.92,均显著性高于对照组的4.62±1.74与4.55±2.85(P<0.05)。术后7d、14d、21d观察组患者CSS评分分别为28.3±6.1、20.1±6.9与13.5±6.1,均显著性低于对照组的34.8±5.7、30.9±6.5与27.5±7.8(P<0.05)。结论使用微创血肿清除术联合亚低温治疗HICH具有明显的疗效,同时对患者的预后具有较为明显的改善作用,值得临床推广使用。 Objective To investigate the clinical efficacy of micro-invasive evacuation of intracranial hematoma combined with mild hypothermia therapy on hypertension-induced cerebral hemorrhage(HICH).Methods 51 patients with HICH were randomly divided into observation group(26cases)and control group(25cases).Patients in observation group received the treatment of micro-invasive evacuation of intracranial hematoma combined with mild hypothermia therapy,while others only received micro-invasive evacuation of intracranial hematoma.The curative effect,Glasgow coma scale score(GCS)and nerve function defect score(CSS)were compared.Results The curative rate and total effective rate in the observation group were23.1% and 88.5%,which were significantly higher than 4.0% and 88.5%in the control group(P<0.05).On the 7th day and 14 th day after operation,the GCS scores of observation group were 6.77±1.80 and 9.38±2.92 significantly higher than4.62±1.74 and 4.55±2.85 of control group(P<0.05);And on the 7th,14 th and 21 st day after operation,the CSS scores in observation group were 28.3±6.1,20.1±6.9and 13.5±6.1,which were significantly lower than 34.8±5.7,30.9±6.5and 27.5±7.8in the control group(P<0.05).Conclusion The treatment of micro-invasive evacuation of intracranial hematoma combined with mild hypothermia therapy has obvious curative effect on HICH,and improves the prognosis of patients.It is worthy of further clinical application.
作者 张惠阳
出处 《中国实用神经疾病杂志》 2016年第9期19-21,共3页 Chinese Journal of Practical Nervous Diseases
关键词 颅内血肿 微创清除术 亚低温 高血压脑出血 Intracranial hematoma Micro-invasive evacuation Low temperature Hypertensive intracerebral hemorrhage
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