摘要
皮肤和毛囊中黑色素细胞产生的真黑素和褐黑素的分布和数量比例决定着哺乳动物的毛色,色素表型在黑色素合成的不同阶段受多个基因的调控。MC1R基因和ASIP基因是影响黑色素合成的两个重要基因,在黑色素合成和毛色调控过程中起关键作用。MC1R基因的表达产生真黑素,而ASIP基因则通过负调控机制增加褐黑素的生成。文章对近年来与绵羊毛色性状紧密相关的MC1R基因和ASIP基因的研究进展进行综述,旨在增进对绵羊毛色形成机理的了解,为绵羊育种与生产提供理论参考。
The amount ratio of eumelanin and pheomelanin produced by melanocytes in skin and hair follicles determines the coat color of mammals.Color phenotypes are regulated by multiple genes at different stages of melanin synthesis.MC1 R and ASIP genes are two important genes that affect melanin synthesis and play key roles in melanin synthesis and coat color regulation.The expression of MC1 R gene produces eumelanin,while ASIP gene increases the production of pheomelanin through negative regulatory mechanism.This paper reviewed the research progress of MC1 R and ASIP genes,which are closely related to wool color traits,in order to improve the understanding of the formation mechanism of wool color and to provide theoretical reference for the breeding and production of sheep.
作者
孙晓燕
付琳
陈灿灿
任航行
SUN Xiaoyan;FU Lin;CHEN Cancan;REN Hangxing(Chongqing Academy of Animal Sciences,Chongqing 402460,China;College of Animal Science and Technology,Gansu Agricultural University,Lanzhou 730070,China)
出处
《黑龙江畜牧兽医》
CAS
北大核心
2019年第17期41-44,共4页
Heilongjiang Animal Science And veterinary Medicine
基金
重庆市科研院所绩效激励引导专项(cstc2018jxjl80001)
国家自然科学基金项目(31672393)
重庆市农发资金项目(15404)
关键词
绵羊
毛色
基因
色素表型
调控机制
sheep
coat color
gene
color phenotype
regulatory mechanism
