摘要
肝移植是治疗终末期肝病最有效的手段。但由于该类患者自身极其复杂的病理生理状态,加之手术打击,常常导致术中术后出现缺血再灌注综合征(IRS),影响手术效果,甚至危及患者生命。目前相关机制尚未完全得到阐述,防治手段也没有统一的方案。本文就IRS的临床定义、相关病理生理改变、发病机制及治疗手段的最新研究进展进行综述回顾。
Liver transplantation has been considered as the most effective method for the treatment of end-stage liver disease.Ischemia reperfusion syndrome(IRS),a type of lethal complication associated with liver transplantation,may occur in the intraoperative and/or postoperative period due to the poor situation of patient and operation.However,the underlying mechanisms and treatment have not been clearly stated.In this article,we reviewed the advances associated with underlying mechanisms and treatment of IRS.
出处
《武汉大学学报（医学版）》
CAS
2018年第1期16-19,共4页
Medical Journal of Wuhan University
关键词
缺血再灌注综合征
肝移植
血流动力学紊乱
Ischemia Reperfusion Syndrome
Liver Transplantation
Hemodynamic Disturbance
