摘要
慢性肾脏病(CKD)发病率逐年升高,有效治疗手段缺乏,患者在疾病终末期需接受肾替代治疗。目前,干细胞疗法作为研究热点已被运用于修复多种受损组织器官。研究表明骨髓间充质干细胞(BMSCs)对慢性肾脏病的治疗也起到了确切效果,具有一定治疗前景,且可与多种因素联合治疗显著提高疗效。本文就近年来骨髓间充质干细胞在治疗慢性肾脏病研究进展做一综述。
Chronic kidney disease(CKD) is a kind of common clinical disease with rising morbidity. However,no effective therapy modes have been developed to treat CKD. The patients have to accept continuous renal replacement therapy at the end stage of the disease. At present, stem cell therapies as the research focus have been applied to repair many damaged tissues and organs. The curative effect of bone marrow-derived mesenchymal stem cells(BMSCs) on CKD has also been reported by researchers. BMSCs as a promising therapeutic method can also be combined with other factors to achieve better treatment effect. This paper reviews the progress in research on role of BMSCs in the treatment of CKD in recent years.
出处
《海南医学》
CAS
2016年第6期968-972,共5页
Hainan Medical Journal
基金
云南省科技厅-昆明医科大学应用基础研究联合专项(编号:2012FB047)
云南省教育厅科学研究基金重点项目(编号:2012Z083)
关键词
慢性肾脏病
骨髓间充质干细胞
肾替代
干细胞疗法
Chronic kidney disease(CKD)
Bone marrow-derived mesenchymal stem cells(BMSCs)
Renal re placement
Stem cell therapy
