摘要
目的 :评价维持性血液透析 (HD)病人庚型、丙型和乙型肝炎病毒感染状况和危险因子。方法 :应用第二代ELISA方法对 10 5例本院HD病人进行HGV、HCV和HBV检则 ,并与透析时间、输血次数等关系进行对比分析。结果 :10 5例HD病人肝炎感染率分别为 :HGV 14.3%、HCV 5 1.4%、HBV 2 2 .9% ,均明显高于对照组 (P <0 .0 5～ <0 .0 1)。其中HCV感染率与透析时间、输血次数相关程度密切 (P <0 .0 0 1) ,且输血次数相对危险性 (OR =2 .735 1)大于透析年度 (OR =2 .0 315 )。结论 :透析环境是HD病人感染HGV、HCV和HBV的危险因子 ,其中HCV感染率随透析年度增加呈增高趋势 ,可能是通过共用透析机和重复透析器传播。输血仍是感染HCV另一重要危险因子 。
Objective:In order to estimate condition and risk dangerous of hepatitis G virus ,hepatitis C virus and hepatitis B virus infection in maintenance hemodialysis patients.Methods:The infection rates of hepatitis in 105 HD patients were 105 HD patients were evaluated by using ELISA to detect serum anti-HGV antibodies, anti-HCV antibodies and anti-HBV antibodies. The ralationship were analysised among times of HD, frequence of hematometachysis and HGV, HCV,HBV infection.Results:HGV(14.3%), HCV(51.4%), HBV(22.9%). The infection rates of hepatitis was significantly higher than that in control group(P<0.05～0.01).Among them, The infection rates of HCV was related to times of HD and frequence of hematometachysis (P<0.001). The dangerous of frequence of hematometachysis were higher than year of HD.conclusion:The risk factor of hepatitis was environment of HD. The infection rates of HCV was increased with year of HD.The ways of infection were factors of repeated using of dialyzer and dialysis machine. Hematometachysis was one of the dangerous factor with the infection of HCV.
出处
《中国中西医结合肾病杂志》
2002年第11期640-642,共3页
Chinese Journal of Integrated Traditional and Western Nephrology
