摘要
目的:通过研究早期动脉血乳酸水平及乳酸清除率,分析在AIDS合并马尔尼菲篮状菌病患者中的监测价值。方法:回顾性分析2017年我院收治的AIDS患者46例,根据患者的疾病转归分为存活组和死亡组,其中存活组31例、死亡组15组。比较两组患者的年龄、性别,分别检测患者在入院时、入院治疗6 h的动脉血乳酸水平,计算患者6 h乳酸清除率。结果:两组年龄、性别比较差异无统计学意义(P>0.05);存活组在入院时、入院治疗6h的动脉血乳酸水平低于死亡组,而且存活组的乳酸清除率高于死亡组(均P<0.05)。结论:AIDS合并马尔尼菲篮状菌病患者早期的动脉血乳酸水平越高,6 h的乳酸清除率越低,提示患者的病情越重、预后越差,监测有着重要价值。
Objective:To investigate the value of early arterial blood lactatelevel and lactate clearance in monitoring the patient condition of AIDS complicated with Talaromycosis marneffei(TSM).Methods:This was a retrospective study on 46 AIDS patients admitted to our hospital in 2017.According to the outcome of their condition,the patients were divided into the survival group(n=31)and death group(n=15).The two groups were compared for age and sexproportion,level of arterial blood lactate and lactate clearance at the time of admissionandat6 h later.The 6 hlactate clearance was calculated.Results:There were no significant differences in age and sex proportion between the two groups(P>0.05).The survival group presented lower arterial blood lactate level and higher lactate clearance at the time of admission and at 6 h later than did the death group(all P<0.05).Conclusion:Higher level of early arterial blood lactate and lower 6 h lactate clearance may suggest more severe patient condition and worse prognosis in TSM-complicated AIDS,and are therefore of great value in monitoring of the disease.
作者
冯凯
黄齐
林焕兴
李粤平
李凌华
Feng Kai;Huang Qi;Lin Huanxing;Li Yueping;Li Linghua(Department of Infectious Diseases,Guangzhou Eighth People’s Hospital,Guangzhou,Guangdong 510060,China)
出处
《广州医科大学学报》
2019年第2期48-50,共3页
Academic Journal of Guangzhou Medical University
基金
“十三五”国家科技重大专项(2018ZX10302104-001-007)
关键词
早期动脉血乳酸
乳酸清除率
AIDS
马尔尼菲篮状菌
监测
early arterial blood lactatelevel
lactate clearance
AIDS
talaromycosis marneffei
monitoring
