摘要
目的 :为研究霉菌性食管炎的诊断与治疗。方法 :本组 4 5 0例均经电子胃镜检查 ,病理证实 ,依食管黏膜损害程度分为重、中、轻三度 ,并依次口服三联法 (洛赛克或西咪替丁、盐酸黄连素、西沙必利 ) 2 5 0例 ,单服克霉唑 10 0例 ,食用大蒜 10 0例 ,各组治疗均依每 10d为 1疗程 ,若无毒副反应可连用 2疗程 ,并经内镜、病理复检无显示念珠菌为治愈。结果 :三联法治愈占 98% ,克霉唑占 5 3% ,食用大蒜法占 5 4 % ,另有 10 %为自愈。经统计学处理结果表明 ,三联法治愈率优于各组 (P <0 .0 1) ,而克霉唑与食用大蒜比较无显著差异 (P >0 .0 5 )。结论 :经三联法治疗霉菌性食管炎 ,方法简便、治愈率高、无毒副反应、疗程短 ,且适宜推广。
Objective:In order to study the diagnosis and treatment of candiosis esophagitis.Method:Four hundred and fifty cases patients were examed by electric endoscopic and pathologic dignosis, they were divided into three groups (heavy, middle, slight ) according to mucosa damage,triad-therapy (Losec or Cimetidine,berberine hydrochloride and Cisapride) fit heavy group (250 cases),Ciotrimazole fit middle group (100 cases) ,Garlic fit slight group (100 cases) 10 days was one course of treatment, if there were no side effect, patients could accept next course. Results:The cure rate was 98% in triad-therapy group and was 53 % in Clotrimazole group, 10% patients were nature cure.The cure effect of triad-therapy was better than other groups, it had great difference (χ 2= 273.2 , P < 0.01 ) .Clotrimazole and Garlic group had no difference (χ 2=2.43, P >0.05 ).Conclusion:Triad-therapy had well effect and no side effect, it's easily to spread, it's also helpful to divide into different groups according to the incidence characteristic and choose suitable drugs.
出处
《中国内镜杂志》
CSCD
2002年第11期28-29,31,共3页
China Journal of Endoscopy
