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经导管子宫动脉栓塞治疗子宫肌瘤的副反应与并发症分析 被引量:54

Analysis of adverse reactions and complications of transcatheter uterine artery embolization (TUAE) for uterine fibroids
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摘要 目的 探讨经导管子宫动脉栓塞 (TUAE)治疗子宫肌瘤的副反应与并发症及其防治措施。方法  182例子宫肌瘤接受TUAE治疗 ,患者年龄 2 8~ 5 1岁 ,平均 3 9 4岁。TUAE方法为经导管双侧子宫动脉注入超化碘油 平阳霉素乳剂 (LPE) ,然后以明胶海绵颗粒栓塞子宫动脉近端至血流变缓慢。栓塞后住院治疗 3~ 10d ,出院后分别于栓塞后 1个月、3个月、6个月、1年、2年回院复查 ,期间观察副反应与并发症。结果 TUAE的副反应包括不同程度的栓塞后综合征 (182例 ,10 0 % ) ,尿频、尿急、尿痛 (2 4例 ,13 2 % )和阴道少量流血 (2 5例 ,13 7% )。TUAE的并发症则包括阴道排泄坏死肌瘤组织 (5例 ,2 8% ) ,尿潴留 (10例 ,5 5 % ) ,尿路感染 (1例 ,0 5 % ) ,小阴唇溃疡 (1例 ,0 5 % ) ,臂部淤血、溃烂 (1例 ,0 5 % )和卵巢囊肿继发感染 (1例 ,0 5 % )。以上TUAE的副作用经对症或特别处理后均恢复正常 ,无后遗症发生。结论 TUAE的副反应是可逆的 。 Objective To investigate the adverse reactions and complications as well as their preventive and therapeutic measures of TUAE for uterine fibroids Methods One hundred and eighty two patients with uterine fibroids were treated by TUAE Bilateral uterine arteries were embolized using lipiodol pingyangmycin emulsion (LPE), together with Gelfoam particles All patients were hospitalized for 3 to 10 days after TUAE and were followed up for 1 to 24 months to observe the adverse reactions and complications Results Adverse reactions of TUAE included postembolization syndrome ( n =182); urinary irritation ( n =24), and hyporrhea of vagina ( n =25) Complications of TUAE included expelling of necrotic fibroids per vagina ( n =5); urinary retention ( n =10); urinary tract infection ( n =1); ulcer of labia minora ( n =1); ecchymosis and ulceration on buttock ( n =1), and secondary infection of chocolate cyst of ovary ( n =1) All the above mentioned side effects of TUAE recovered to normal after expectant or especial treatment without any sequels left Conclusion The adverse reactions of TUAE are reversible and the complications of TUAE are preventable and curable
出处 《中华放射学杂志》 CAS CSCD 北大核心 2002年第12期1087-1090,共4页 Chinese Journal of Radiology
关键词 子宫肿瘤 治疗性栓塞 手术后并发症 治疗 Uterine neoplasms Embolization, therapeutic Postoperative complications
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