摘要
目的分析高曲率近视患者行飞秒激光辅助原位角膜磨镶术(FS-LASIK)和准分子激光上皮下角膜磨镶术(LASEK)屈光术后对患者角膜、前房形态变化的影响。方法选取2021年5月至2022年2月在本院行屈光手术治疗的75例(150眼)近视患者纳入研究。根据角膜前表面陡峭曲率将其分为正常曲率组(30例60眼)和高曲率组(45例90眼)。所有患者均进行FS-LASIK或LASEK屈光手术治疗。术后对患者进行为期1年的随访,比较两组临床疗效、角膜形态、前房形态、眼表状态及安全性。结果两组临床疗效及安全性比较差异无统计学意义(P>0.05)。两组术前、术后1、3、12个月的角膜后表面高度、中央前房深度(ACD)、前房容积(ACV)、房角宽度(ACA)及术后12个月与术前变化量比较差异均无统计学意义(P>0.05)。两组术后1个月、3个月、12个月与术前后表面曲率变化量比较差异均无统计学意义(P>0.05)。两组术后泪膜破裂时间(BUT)、基础泪液分泌实验(LST)下降,角膜荧光素染色实验(FL)、眼表疾病指数(OSDI)升高(P<0.05),但观察组与对照组比较差异无统计学意义(P>0.05)。结论单纯高曲率和正常曲率近视患者临床进行FS-LASIK或LASEK治疗,患者术后均可达到安全、有效的手术效果。
ObjectiveTo analyze the morphological changes of cornea and anterior chamber after femtosecond laser-assisted in situ keratomileusis(FS-LASIK)and laser subepithelial keratomileusis(LASEK)in high curvature myopic eyes.MethodsA total of 75 myopic patients(150 eyes)who underwent refractive surgery in the hospital from May 2021 to February 2022 were included in the study.According to corneal curvature,the patients were divided into control group(normal curvature,30 cases)and observation group(high curvature,45 cases).All patients were treated with FS-LASIK or LASEK refractive surgery.The patients were followed up for 1 year after surgery.The clinical efficacy,corneal morphology,anterior chamber morphology,ocular surface status and safety were compared between the 2 groups.ResultsThere was no significant difference in clinical efficacy and safety between the 2 groups(P>0.05).There was no significant difference in anterior chamber depth(ACD),anterior chamber volume(ACV)and anterior chamber angle width between the 2 groups before the surgery,1,3,and 12 months after the surgery,and the change of anterior chamber angle width between 12 months after the surgery and before thesurgery(P>0.05).There was no significant difference in the change of posterior surface curvature between the 2 groups at 1 month,3 months and 12 months after the operation and before the operation(P>0.05).The tear film break-up time(BUT)and schirmer's test(LST)in the 2 groups were decreased,while corneal fluorescein staining(FL)and ocular surface disease index(OSDI)was increased after surgery(P<0.05),but there was no significant difference between the observation group and the control group(P>0.05).ConclusionBoth FS-LASIK and LASEK are safe and effective for myopia patients with high and normal curvature.
作者
崔燕
刘红杰
张珍珍
张亚娟
韩君
任延军
CUI Yan;LIU Hongjie;ZHANG Zhenzhen;ZHANG Yajuan;HAN Jun;REN Yanjun(Department of Refractive Surgery,Handan Eye Hospital,Handan Hebei 056001,China)
出处
《新疆医科大学学报》
CAS
2024年第12期1627-1631,共5页
Journal of Xinjiang Medical University
基金
河北省卫生健康委项目青年科技课题项目(20210806)。
关键词
飞秒激光辅助原位角膜磨镶术
准分子激光上皮下角膜磨镶术
高曲率近视
角膜形态
前房形态
安全性
femtosecond laser-assisted in situ keratomileusis(FS-LASIK)
laser subepithelial keratomileusis(LASEK)
high curvature myopia
corneal form
anterior chamber form
safety
