摘要
目的:对比新血宝胶囊与右旋糖酐铁分别联合维生素C治疗妊娠贫血的临床效果。方法:选取2021年1月—2023年12月揭阳市揭西县钱坑镇卫生院收治的70例妊娠贫血患者为研究对象,随机分为对照组及观察组,各35例。对照组采用右旋糖酐铁联合维生素C治疗,观察组采用新血宝胶囊联合维生素C治疗。对比两组临床疗效、贫血指标、网织红细胞指标、不良反应发生情况及妊娠结局。结果:观察组治疗总有效率高于对照组(P=0.046);治疗后,两组血红蛋白、红细胞计数、红细胞平均体积、红细胞平均血红蛋白、平均血红蛋白浓度水平均升高,观察组高于对照组(P<0.05);治疗后,两组网织红细胞绝对值、单个网织红细胞内平均血红蛋白浓度升高,未成熟网织红细胞比率降低,观察组优于对照组(P<0.05)。两组不良反应发生率及不良妊娠结局发生率对比,无统计学差异(P>0.05)。结论:新血宝胶囊联合维生素C可改善妊娠期缺铁性贫血患者的贫血指标及网织红细胞参数,治疗效果优于右旋糖酐铁联合维生素C,且安全性尚可。
Objective:To compare the clinical effect of Xinxuebao capsule and iron dextran combined with vitamin C in the treatment of anemia in pregnancy.Methods:A total of seventy patients with anemia of pregnancy admitted to Jieyang Jiexi County Qiankeng Town Health Center from January 2021 to December 2023 were selected as the study objects,and randomly divided into control group and observation group,with thirty-five cases in each group.The control group was treated with iron dextran combined with vitamin C,and the observation group was treated with Xinxuebao capsule combined with vitamin C.The clinical efficacy,anemia index,reticulocyte index,occurrence of adverse reactions and pregnancy outcome were compared between the two groups.Results:The total effective rate of observation group was higher than that of control group(P=0.046);after treatment,hemoglobin,red blood cell count,mean volume of red blood cell,mean hemoglobin of red blood cell and mean hemoglobin concentration of two groups were increased,and the observation group was higher than the control group(P<0.05);after treatment,the absolute value of two reticulocytes and the mean hemoglobin concentration in single reticulocyte increased,and the ratio of immature reticulocyte decreased,and the observation group was better than the control group(P<0.05);there was no significant difference in the incidence of adverse reactions and adverse pregnancy outcomes between the two groups(P>0.05).Conclusion:Xinxuebao capsule combined with vitamin C can improve the anemia indexes and reticulocyte parameters of the patients with iron deficiency anemia during pregnancy,and the therapeutic effect is better than that of iron dextroanhydride combined with vitamin C,and the safety is reasonable.
作者
李巧芬
Li Qiaofen(Department of Obstetrics and Gynecology,Jieyang Jiexi County Qiankeng Town Health Center,Jieyang 515432,Guangdong Province,China)
出处
《中外医药研究》
2024年第32期76-78,共3页
JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH
