摘要
目的了解吸毒人员LTBI情况及影响因素,为制定结核病防治策略提供依据。方法采用TST,筛查289名吸毒人员LTBI情况。以硬结平均直径≥5mm或局部出现双圈、水泡、坏死及淋巴管炎为TST阳性。以性别、年龄、民族、文化程度、毒品种类、吸毒方式、吸毒时长、是否有艾滋病史、糖尿病史、病毒性肝炎史、呼吸系统疾病史、冠心病史、高血压史和结核病接触史为自变量,是否发生LTBI为因变量,采用二元logistic回归分析LTBI的影响因素。结果289名吸毒人员中,LTBI人数119名,感染率41.2%。多因素分析显示混合吸食毒品和患高血压的人员更易发生LTBI。结论吸毒人员LTBI感染率较高,应重视戒毒人员结核病的防治,必要时采取预防性治疗。
Objective To understand the infection status and influencing factors of latent tuberculosis infection(LTBI)in drug users,so as to provide basis for the formulation of tuberculosis prevention and control strategy.Methods Tuberculin skin test(TST)was screened in 289 drug users.The average diameter of induration≥5mm or the local double ring,blisters,necrosis and lymphangitis were TST-positive.Gender,age,ethnicity,education level,drug use type,drug use pattern,drug use duration,history of AIDS,diabetes,viral hepatitis,respiratory diseases,coronary heart disease,hypertension and TB exposure were independent variables,and the occurrence of LTBI was dependent variable,binary logistic regression analysis was used to analyze the influencing factors of LTBI.Results Among the 289 drug users,119 were LTBI,with an infection rate of 41.2%.Multivariate analysis showed that people with mixed drug use and hypertension were more prone to LTBI.Conclusions The infection rate of LTBI in drug users is higher,so we should pay more attention to the prevention and treatment of tuberculosis for the patients abstained from drugs,and take preventive treatment if necessary.
作者
张红吉
马仲序
刁婷婷
刘超
李晓非
ZHANG Hongji;MA Zhongxu;DIAO Tingting;LIU Chao;LI Xiaofei(Department of General Medicine,Kunming Third People's Hospital/Yunnan Provincial Clinical Medical Center for Infectious Diseases,Kunming Yunnan 650041,China;Department of Science and Education and Academic,Kunming Third People's Hospital/Yunnan Provincial Clinical Medical Center for Infectious Diseases,Kunming Yunnan 650041,China;Public Health School of Dali University,Dali Yunnan 671000,China;School of Public Health and Health Management,Qujing Medical College,Qujing Yunnan 655000,China)
出处
《云南医药》
CAS
2024年第6期34-37,共4页
Medicine and Pharmacy of Yunnan
基金
地方高校联合专项资助项目(202001BA070001-136)。
关键词
结核潜伏感染
结核分枝杆菌
吸毒人员
影响因素
latent tuberculosis infection(LTBI)
mycobacterium tuberculosis
drug addict
influencing factors
