摘要
天然产物化学实验是基于理论课基础上的一门重要实践课程,以验证为主的实验课缺少高阶性,不利于学生综合能力的提升。因此,通过将科研新成果融入课程的综合实验设计,融入“双碳”理念,强化课程的“两性一度”。该实验将高荧光强度的光动力抑菌食品包装膜的前沿研究融入到天然产物化学实验中,首次将天然聚集诱导发光剂盐酸小檗碱与植酸结合成盐加入到食品包装膜中,构建了一种具有高荧光强度的光动力抑菌膜。本实验融合了天然产物化学、聚集诱导发光和食品微生物学的内容,并推动学生熟悉原理-实验-表征-分析的科研流程,实质性丰富学生的综合知识,强化学生实践能力和创新意识,助力林产化工专业拔尖人才的培养。
Natural products chemistry experiment courses are vital practical part built upon theoretical foundations.However,these verification-focused experiments lack depth and hinder the development of students' comprehensive abilities.To address this issue,we proposed integrating new scientific research findings into the design of comprehensive experiments,incorporating the concept of “double carbon”,and enhancing the depth of the course.In this experiment,we introduced cutting-edge research on photodynamic antimicrobial food packaging films with high fluorescence intensity into natural product chemistry experiments.Specifically,we incorporated berberine hydrochloride,a naturally occurring aggregation-induced emission agent,with phytic acid to create a salt that was added to the food packaging film,resulting in a photodynamic antimicrobial film with strong fluorescence.This experiment combined the fields of natural product chemistry,aggregation-induced emission,and food microbiology,and encouraged students to become familiar with the research process of theory-experiment-characterizationanalysis.Through this integration,students could enrich their comprehensive knowledge,strengthen their practical skills,and foster their innovation consciousness,thus contributing to the cultivation of top talents in the field of forest chemical industry.
作者
王立娟
宁语苹
李坚
罗沙
罗雄飞
王睿文
Lijuan Wang;Yuping Ning;Jian Li;Sha Luo;Xiongfei Luo;Ruiwen Wang(Materials Science and Engineering,Northeast Forestry University,Harbin 150040,China.)
出处
《大学化学》
CAS
2024年第11期241-250,共10页
University Chemistry
基金
东北林业大学教育教学改革项目(DGY2022-14)。
关键词
天然产物化学实验
科教融合
盐酸小檗碱
荧光增强
活性氧
Natural product chemistry experiments
Integration of science and education
Berberine hydrochloride
Fluorescence enhancement
Reactive oxygen species
