摘要
目的探讨血小板平均体积/淋巴细胞比值(MPVLR)对人工髋关节置换术后深静脉血栓(DVT)发生的预测价值。方法选取2022年11月至2023年11月在川北医学院附属医院行人工髋关节置换术的104例患者作为研究对象,根据104例患者是否发生DVT,将其分为DVT组(36例)和非DVT组(68例)。所有患者入院后使用全自动血细胞分析仪检测血小板平均体积(MPV)、淋巴细胞计数(LYC),并计算MPVLR。采用受试者工作特征曲线分析MPV、LYC及MPVLR对人工髋关节置换术后DVT发生的预测价值,采用多因素Logistic回归分析人工髋关节置换术后DVT发生的影响因素。结果VTE组MPV、MPVLR高于非VTE组(P<0.05),LYC低于非VTE组(均P<0.05);MPV、LYC预测人工髋关节置换术后DVT发生的曲线下面积(AUC)分别为0.774(95%CI:0.729~0.824)、0.851(95%CI:0.806~0.901),MPVLR预测人工髋关节置换术后DVT发生的AUC为0.943(95%CI:0.898~0.993);DVT组体质量指数、术后卧床时间≥3 d比例均高于非DVT组(P<0.05);体质量指数≥22.73 kg/m^(2)(OR=1.923,95%CI:1.237~2.989),术后卧床时间≥3 d(OR=2.380,95%CI:1.380~4.104),MPV≥9.65 fL(OR=2.563,95%CI:1.548~4.241),LYC≤1.70×10^(9)/L(OR=2.208,95%CI:1.404~3.472),MPVLR≥5.95(OR=2.942,95%CI:1.816~4.764)是人工髋关节置换术后DVT发生的危险因素(P<0.05)。结论高MPVLR是人工髋关节置换术后DVT发生的危险因素之一,可作为预测人工髋关节置换术后是否发生DVT的重要指标,且预测效能极佳。
Objective To investigate the value of mean platelet volume/lymphocyte ratio(MPVLR)in predicting the occurrence of deep vein thrombosis(DVT)after artificial hip replacement surgery.Methods A total of 104 patients who underwent artificial hip replacement surgery in Affiliated Hospital of North Sichuan Medical College from November 2022 to November 2023 were selected as the research objects.According to whether or not they had DVT,104 patients were divided into DVT group(36 cases)and non-DVT group(68 cases).The mean platelet volume(MPV)and lymphocyte count(LYC)were measured by automatic blood cell analyzer in all patients after admission,and MPVLR was calculated.Receiver operating characteristic curve was used to analyze the predictive value of MPV,LYC,and MPVLR for the occurrence of DVT after artificial hip replacement surgery.Multivariate Logistic regression analysis was used to explore the influencing factors of DVT after artificial hip replacement surgery.Results MPV and MPVLR in VTE group were higher than those in non-VTE group(P<0.05),and LYC was lower than that in non-VTE group(P<0.05).The area under the curve(AUC)of MPV and LYC for predicting DVT after artificial hip arthroplasty were 0.774(95%CI:0.729-0.824)and 0.851(95%CI:0.806-0.901),respectively.AUC of MPVLR for predicting DVT after artificial hip replacement surgery was 0.943(95%CI:0.898-0.993).The body mass index and the proportion of postoperative bed rest time≥3 days in the DVT group were higher than those in the non-DVT group(P<0.05).Body mass index≥22.73 kg/m^(2)(OR=1.923,95%CI:1.237-2.989),postoperative bed rest time≥3 days(OR=2.380,95%CI:1.380-4.104),MPV≥9.65 fL(OR=2.563,95%CI:1.548-4.241),LYC≤1.70×10^(9)/L(OR=2.208,95%CI:1.404-3.472),MPVLR≥5.95(OR=2.942,95%CI:1.816-4.764)were the risk factors for DVT after artificial hip replacement surgery(P<0.05).Conclusion High MPVLR is one of the risk factors for DVT after artificial hip replacement surgery.It could be used as an important indicator to predict the occurrence of DVT after artific
作者
蒲颖
张锐
张露
杨辰菲
胡可芹
PU Ying;ZHANG Rui;ZHANG Lu;YANG Chenfei;HU Keqin(School of Nursing,North Sichuan Medical College,Nanchong,Sichuan 637000,China;Department of Orthopedics,Affiliated Hospital of North Sichuan Medical College,Nanchong,Sichuan 637000,China)
出处
《国际检验医学杂志》
CAS
2024年第24期3010-3014,共5页
International Journal of Laboratory Medicine
基金
四川省医学青年创新科研课题(Q210077)
川北医学院校级科研发展计划项目(CBY-QB11)。
